A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling
Do LNH, Delgado E, Lim CG, Bkhache M, Peluzzo AM, Hua Y, Oza M, Mohsin S, Chen H, Autieri MV, Kim S, Liu X. A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling. Development. 2024 Nov 15;151(22):dev202901. doi: 10.1242/dev.202901. Epub 2024 Nov 26. PMID: 39470100; PMCID: PMC11634036. 

Mitochondrial fission inhibition protects against hypertension induced by angiotensin II
Preston KJ, Kawai T, Torimoto K, Kuroda R, Nakayama Y, Akiyama T, Kimura Y, Scalia R, Autieri MV, Rizzo V, Hashimoto T, Osei-Owusu P, Eguchi S. Mitochondrial fission inhibition protects against hypertension induced by angiotensin II. Hypertens Res. 2024 May;47(5):1338-1349. doi: 10.1038/s41440-024-01610-0. Epub 2024 Feb 21. PMID: 38383894.

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development
Lu Y, Sun Y, Saaoud F, Shao Y, Xu K, Jiang X, Wu S, Yu J, Snyder NW, Yang L, Shi XM, Zhao H, Wang H, Yang X. ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development. Front Immunol. 2023 Sep 4;14:1268916. doi: 10.3389/fimmu.2023.1268916. PMID: 37731512; PMCID: PMC10507336. 

Neuronal AR Regulates Glucose Homeostasis and Energy Expenditure in Lean Female Mice With Androgen Excess
Ubba V, Joseph S, Awe O, Jones D, Dsilva MK, Feng M, Wang J, Fu X, Akbar RJ, Bodnar BH, Hu W, Wang H, Yang X, Yang L, Yang P, Ahima R, Divall S, Wu S. Neuronal AR Regulates Glucose Homeostasis and Energy Expenditure in Lean Female Mice With Androgen Excess. Endocrinology. 2023 Sep 23;164(11):bqad141. doi: 10.1210/endocr/bqad141. PMID: 37738624. 

Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis
Xu K, Saaoud F, Shao Y, Lu Y, Wu S, Zhao H, Chen K, Vazquez-Padron R, Jiang X, Wang H, Yang X. Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis. Redox Biol. 2023 Aug;64:102771. doi: 10.1016/j.redox.2023.102771. Epub 2023 Jun 16. PMID: 37364513; PMCID: PMC10310484.  

Genetic Deletion of FXR1 Reduces Intimal Hyperplasia and Induces Senescence in Vascular Smooth Muscle Cells
Corbett CB, St Paul A, Leigh T, Kelemen SE, Peluzzo AM, Okune RN, Eguchi S, Haines DS, Autieri MV. Genetic Deletion of FXR1 Reduces Intimal Hyperplasia and Induces Senescence in Vascular Smooth Muscle Cells. Am J Pathol. 2023 May;193(5):638-653. doi: 10.1016/j.ajpath.2023.01.006. PMID: 37080662; PMCID: PMC10155270. 

INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10
Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X. INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10. Circulation. 2023 Jul 4;148(1):47-67. doi: 10.1161/CIRCULATIONAHA.123.063760. Epub 2023 May 18. PMID: 37199168; PMCID: PMC10330325. 

FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms
St Paul A, Corbett C, Peluzzo A, Kelemen S, Okune R, Haines DS, Preston K, Eguchi S, Autieri MV. FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms. Cell Rep. 2023 Apr 25;42(4):112381. doi: 10.1016/j.celrep.2023.112381. Epub 2023 Apr 11. PMID: 37043351; PMCID: PMC10564969.  

CRISPR-Cas9 Long-Read Sequencing for Mapping Transgenes in the Mouse Genome
Bryant WB, Yang A, Griffin SH, Zhang W, Rafiq AM, Han W, Deak F, Mills MK, Long X, Miano JM. CRISPR-Cas9 Long-Read Sequencing for Mapping Transgenes in the Mouse Genome. CRISPR J. 2023 Apr;6(2):163-175. doi: 10.1089/crispr.2022.0099. PMID: 37071672; PMCID: PMC10123806.  

Promoting Lymphangiogenesis and Lymphatic Growth and Remodeling to Treat Cardiovascular and Metabolic Diseases
Liu X, Cui K, Wu H, Li KS, Peng Q, Wang D, Cowan DB, Dixon JB, Sathish Srinivasan R, Bielenberg DR, Chen K, Wang DZ, Chen Y, Chen H. Promoting Lymphangiogenesis and Lymphatic Growth and Remodeling to Treat Cardiovascular and Metabolic Diseases. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):e1-e10. doi: 10.1161/ATVBAHA.122.318406. Epub 2022 Dec 1. PMID: 36453280; PMCID: PMC9780193. 

MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
Gao P, Gao P, Zhao J, Shan S, Luo W, Slivano OJ, Zhang W, Tabuchi A, LeMaire SA, Maegdefessel L, Shen YH, Miano JM, Singer HA, Long X. MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm. Redox Biol. 2021 May;41:101903. doi: 10.1016/j.redox.2021.101903. Epub 2021 Feb 20. PMID: 33667992; PMCID: PMC7937568.