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Lewis Katz School of Medicine
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Recent Publications

Bold: Fels members

Bold italics: FCCC adjuncts (publication listed only when first or last author is from FCCC)

Selected Publications (2020-2022) 

2022

  1. Allen CNS, Arjona SP, Santerre M, De Lucia C, Koch WJ, Sawaya BE. Metabolic Reprogramming in HIV-Associated Neurocognitive Disorders. Front Cell Neurosci. 2022;16:812887. Epub 20220328. doi: 10.3389/fncel.2022.812887. PubMed PMID: 35418836; PMCID: PMC8997587.
     
  2. Allen CNS, Arjona SP, Santerre M, Sawaya BE. Hallmarks of Metabolic Reprogramming and Their Role in Viral Pathogenesis. Viruses. 2022;14(3). Epub 20220314. doi: 10.3390/v14030602. PubMed PMID: 35337009; PMCID: PMC8955778.
     
  3. Allen CNS, Santerre M, Arjona SP, Ghaleb LJ, Herzi M, Llewellyn MD, Shcherbik N, Sawaya BE. SARS-CoV-2 Causes Lung Inflammation through Metabolic Reprogramming and RAGE. Viruses. 2022;14(5). Epub 20220506. doi: 10.3390/v14050983. PubMed PMID: 35632725; PMCID: PMC9143006.
     
  4. Basu J, Zha J, Nicolas E, Coulton M, Czyzewicz P, Hua X, Ge L, Kappes DJ. An autonomous TCR signal-sensing switch influences CD4/CD8 lineage choice in mice. Commun Biol. 2022;5(1):84. Epub 20220121. doi: 10.1038/s42003-022-02999-5. PubMed PMID: 35064205; PMCID: PMC8783009.
     
  5. Bhatnagar S, Revuri V, Shah M, Larson P, Shao Z, Yu D, Prabha S, Griffith TS, Ferguson D, Panyam J. Combination of STING and TLR 7/8 Agonists as Vaccine Adjuvants for Cancer Immunotherapy. Cancers (Basel). 2022;14(24). Epub 20221211. doi: 10.3390/cancers14246091. PubMed PMID: 36551577; PMCID: PMC9777055.
     
  6. Borriello L, Coste A, Traub B, Sharma VP, Karagiannis GS, Lin Y, Wang Y, Ye X, Duran CL, Chen X, Friedman M, Sosa MS, Sun D, Dalla E, Singh DK, Oktay MH, Aguirre-Ghiso JA, Condeelis JS, Entenberg D. Primary tumor associated macrophages activate programs of invasion and dormancy in disseminating tumor cells. Nat Commun. 2022;13(1):626. Epub 20220202. doi: 10.1038/s41467-022-28076-3. PubMed PMID: 35110548; PMCID: PMC8811052.
     
  7. Braun A, Abbosh PH. Muscle-invasive Bladder Cancer Arising After Prostate Radiotherapy: A Rare Entity with Unique Genomic Features. Eur Urol. 2022;81(5):474-5. Epub 20220131. doi: 10.1016/j.eururo.2022.01.031. PubMed PMID: 35109971.
     
  8. Chang HW, Feofanov AV, Lyubitelev AV, Armeev GA, Kotova EY, Hsieh FK, Kirpichnikov MP, Shaytan AK, Studitsky VM. N-Terminal Tails of Histones H2A and H2B Differentially Affect Transcription by RNA Polymerase II In Vitro. Cells. 2022;11(16). Epub 20220810. doi: 10.3390/cells11162475. PubMed PMID: 36010552; PMCID: PMC9406932.
     
  9. Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Di Schiavi E, Gatti M, Artandi SE, Raffa GD. TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration. Nucleic Acids Res. 2022;50(21):12400-24. doi: 10.1093/nar/gkac659. PubMed PMID: 35947650; PMCID: PMC9757054.
     
  10. Chow HY, Karchugina S, Groendyke BJ, Toenjes S, Hatcher J, Donovan KA, Fischer ES, Abalakov G, Faezov B, Dunbrack R, Gray NS, Chernoff J. Development and Utility of a PAK1-Selective Degrader. J Med Chem. 2022;65(23):15627-41. Epub 20221123. doi: 10.1021/acs.jmedchem.2c00756. PubMed PMID: 36416208.
     
  11. Cukierman E. The Few yet Fab(p4)ulous Pancreatic Stellate Cells Give Rise to Protumoral CAFs. Cancer Discov. 2022;12(2):296-8. doi: 10.1158/2159-8290.Cd-21-1501. PubMed PMID: 35140177.
     
  12. DeAntoneo C, Danthi P, Balachandran S. Reovirus Activated Cell Death Pathways. Cells. 2022;11(11). Epub 20220527. doi: 10.3390/cells11111757. PubMed PMID: 35681452; PMCID: PMC9179526.
     
  13. Demidova EV, Ghatalia P, Arora S. Combination Strategies for Immune Checkpoint Inhibitors in PBRM1-mutant Renal Cell Carcinoma: To PARP or Not To PARP? Eur Urol. 2022;81(2):149-50. Epub 20211106. doi: 10.1016/j.eururo.2021.10.028. PubMed PMID: 34753637.
     
  14. Deneka AY, Baca Y, Serebriiskii IG, Nicolas E, Parker MI, Nguyen TT, Xiu J, Korn WM, Demeure MJ, Wise-Draper T, Sukari A, Burtness B, Golemis EA. Association of TP53 and CDKN2A Mutation Profile with Tumor Mutation Burden in Head and Neck Cancer. Clin Cancer Res. 2022;28(9):1925-37. doi: 10.1158/1078-0432.Ccr-21-4316. PubMed PMID: 35491653; PMCID: PMC9186806.
     
  15. Deneka AY, Nikonova AS, Lee HO, Kruger WD, Golemis EA. NEDD9 sustains hexokinase expression to promote glycolysis. Oncogenesis. 2022;11(1):15. Epub 20220411. doi: 10.1038/s41389-022-00391-w. PubMed PMID: 35410460; PMCID: PMC9001639.
     
  16. Diefenbach MA, Miller SM. How should decision aids be developed, and which patient outcomes should be assessed? Cancer. 2022;128(15):2988-9. Epub 20220504. doi: 10.1002/cncr.34247. PubMed PMID: 35507272; PMCID: PMC9262809.
     
  17. Dolinko AV, Schultz BM, Ghosh J, Kalliora C, Mainigi M, Coutifaris C, Sapienza C, Senapati S. Disrupted methylation patterns at birth persist in early childhood: a prospective cohort analysis. Clin Epigenetics. 2022;14(1):129. Epub 20221015. doi: 10.1186/s13148-022-01348-x. PubMed PMID: 36243864; PMCID: PMC9568969.
     
  18. Drzewiecka M, Barszczewska-Pietraszek G, Czarny P, Skorski T, Śliwiński T. Synthetic Lethality Targeting Polθ. Genes (Basel). 2022;13(6). Epub 20220620. doi: 10.3390/genes13061101. PubMed PMID: 35741863; PMCID: PMC9223150.
     
  19. Fahl SP, Sertori R, Zhang Y, Contreras AV, Harris B, Wang M, Perrigoue J, Balachandran S, Kennedy BK, Wiest DL. Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis. J Immunol. 2022;208(4):870-80. Epub 20220119. doi: 10.4049/jimmunol.2100668. PubMed PMID: 35046107; PMCID: PMC8827804.
     
  20. Fragoso MF, Fernandez GJ, Vanderveer L, Cooper HS, Slifker M, Clapper ML. Dysregulation of miR-1-3p: An Early Event in Colitis-Associated Dysplasia. Int J Mol Sci. 2022;23(21). Epub 20221027. doi: 10.3390/ijms232113024. PubMed PMID: 36361810; PMCID: PMC9657954.
     
  21. Gardiner JC, Cukierman E. Meaningful connections: Interrogating the role of physical fibroblast cell-cell communication in cancer. Adv Cancer Res. 2022;154:141-68. Epub 20220224. doi: 10.1016/bs.acr.2022.01.004. PubMed PMID: 35459467; PMCID: PMC9483832.
     
  22. Gerasimova NS, Volokh OI, Pestov NA, Armeev GA, Kirpichnikov MP, Shaytan AK, Sokolova OS, Studitsky VM. Structure of an Intranucleosomal DNA Loop That Senses DNA Damage during Transcription. Cells. 2022;11(17). Epub 20220828. doi: 10.3390/cells11172678. PubMed PMID: 36078089; PMCID: PMC9454427.
     
  23. Ghosh J, Schultz BM, Chan J, Wultsch C, Singh R, Shureiqi I, Chow S, Doymaz A, Varriano S, Driscoll M, Muse J, Kleiman FE, Krampis K, Issa JJ, Sapienza C. Epigenome-Wide Study Identifies Epigenetic Outliers in Normal Mucosa of Patients with Colorectal Cancer. Cancer Prev Res (Phila). 2022;15(11):755-66. doi: 10.1158/1940-6207.Capr-22-0258. PubMed PMID: 36219239; PMCID: PMC9623234.
     
  24. Gross S, Hooper R, Tomar D, Armstead AP, Shanas N, Mallu P, Joshi H, Ray S, Chong PL, Astsaturov I, Farma JM, Cai KQ, Chitrala KN, Elrod JW, Zaidi MR, Soboloff J. Suppression of Ca(2+) signaling enhances melanoma progression. Embo j. 2022;41(19):e110046. Epub 20220830. doi: 10.15252/embj.2021110046. PubMed PMID: 36039850; PMCID: PMC9531303.
     
  25. Hara T, Kasagi Y, Wang J, Sasaki M, Aaron B, Karami A, Shimonosono M, Shimonosono R, Maekawa H, Dolinsky L, Wilkins B, Klein J, Wei J, Nunes K, Lynch K, Spergel JM, Hamilton KE, Ruffner MA, Karakasheva TA, Whelan KA, Nakagawa H, Muir AB. CD73(+) Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cell Mol Gastroenterol Hepatol. 2022;13(5):1449-67. Epub 20220130. doi: 10.1016/j.jcmgh.2022.01.018. PubMed PMID: 35108658; PMCID: PMC8957025.
     
  26. Harrison S, Judd J, Chin S, Ragin C. Disparities in Lung Cancer Treatment. Curr Oncol Rep. 2022;24(2):241-8. Epub 20220126. doi: 10.1007/s11912-022-01193-4. PubMed PMID: 35080738; PMCID: PMC8965800.
     
  27. Herbert A, Balachandran S. Z-DNA enhances immunotherapy by triggering death of inflammatory cancer-associated fibroblasts. J Immunother Cancer. 2022;10(11). doi: 10.1136/jitc-2022-005704. PubMed PMID: 36450382; PMCID: PMC9716847.
     
  28. Johnson J, Blackman R, Gross S, Soboloff J. Control of STIM and Orai function by post-translational modifications. Cell Calcium. 2022;103:102544. Epub 20220131. doi: 10.1016/j.ceca.2022.102544. PubMed PMID: 35151050; PMCID: PMC8960353.
     
  29. Johnson NM, Parham LR, Na J, Monaghan KE, Kolev HM, Klochkova A, Kim MS, Danan CH, Cramer Z, Simon LA, Naughton KE, Adams-Tzivelekidis S, Tian Y, Williams PA, Leu NA, Sidoli S, Whelan KA, Li N, Lengner CJ, Hamilton KE. Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium. EMBO Rep. 2022;23(11):e55209. Epub 20220919. doi: 10.15252/embr.202255209. PubMed PMID: 36120829; PMCID: PMC9638868.
     
  30. Kabir MF, Karami AL, Cruz-Acuña R, Klochkova A, Saxena R, Mu A, Murray MG, Cruz J, Fuller AD, Clevenger MH, Chitrala KN, Tan Y, Keith K, Madzo J, Huang H, Jelinek J, Karakasheva T, Hamilton KE, Muir AB, Tétreault MP, Whelan KA. Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium. Nat Commun. 2022;13(1):2167. Epub 20220420. doi: 10.1038/s41467-022-29747-x. PubMed PMID: 35443762; PMCID: PMC9021266.
     
  31. Kadariya Y, Sementino E, Shrestha U, Gorman G, White JM, Ross EA, Clapper ML, Neamati N, Miller MS, Testa JR. Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma. Carcinogenesis. 2022. Epub 20221110. doi: 10.1093/carcin/bgac089. PubMed PMID: 36355620.
     
  32. Kadin ME, Morgan J, Wei W, Song Z, Yang Y. CD30 Regulation of IL-13-STAT6 Pathway in Breast Implant Associated Anaplastic Large Cell Lymphoma. Aesthet Surg J. 2022. Epub 20220824. doi: 10.1093/asj/sjac234. PubMed PMID: 35999655.
     
  33. Klochkova A, Fuller AD, Miller R, Karami AL, Panchani SR, Natarajan S, Mu A, Jackson JL, Klein-Szanto AJ, Muir AB, Whelan KA. A role for age-associated alterations in esophageal epithelium in eosinophilic esophagitis-associated fibrosis. Front Allergy. 2022;3:983412. Epub 20221215. doi: 10.3389/falgy.2022.983412. PubMed PMID: 36591561; PMCID: PMC9798296.
     
  34. Koc MA, Asmellash S, Norman P, Rightmyer S, Roder J, Georgantas RW, 3rd, Roder H. Semi-Quantitative MALDI Measurements of Blood-Based Samples for Molecular Diagnostics. Molecules. 2022;27(3). Epub 20220201. doi: 10.3390/molecules27030997. PubMed PMID: 35164262; PMCID: PMC8840133.
     
  35. Kotova EY, Hsieh FK, Chang HW, Maluchenko NV, Langelier MF, Pascal JM, Luse DS, Feofanov AV, Studitsky VM. Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In Vitro. Int J Mol Sci. 2022;23(13). Epub 20220626. doi: 10.3390/ijms23137107. PubMed PMID: 35806109; PMCID: PMC9266421.
     
  36. Kruger WD. How to fix a broken protein: restoring function to mutant human cystathionine β-synthase. Hum Genet. 2022;141(7):1299-308. Epub 20211012. doi: 10.1007/s00439-021-02386-w. PubMed PMID: 34636997; PMCID: PMC9003067.
     
  37. Kurimchak AM, Herrera-Montávez C, Montserrat-Sangrà S, Araiza-Olivera D, Hu J, Neumann-Domer R, Kuruvilla M, Bellacosa A, Testa JR, Jin J, Duncan JS. The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells. Sci Signal. 2022;15(749):eabn2707. Epub 20220830. doi: 10.1126/scisignal.abn2707. PubMed PMID: 36041010; PMCID: PMC9552188.
     
  38. Le BV, Podszywałow-Bartnicka P, Piwocka K, Skorski T. Pre-Existing and Acquired Resistance to PARP Inhibitor-Induced Synthetic Lethality. Cancers (Basel). 2022;14(23). Epub 20221124. doi: 10.3390/cancers14235795. PubMed PMID: 36497275; PMCID: PMC9741207.
     
  39. Liebermann DA. Gadd45 in Normal Hematopoiesis and Leukemia. Adv Exp Med Biol. 2022;1360:41-54. doi: 10.1007/978-3-030-94804-7_3. PubMed PMID: 35505161.
     
  40. Liu H, Lin J, Zhou W, Moses R, Dai Z, Kossenkov AV, Drapkin R, Bitler BG, Karakashev S, Zhang R. KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer. Cancer Immunol Res. 2022;10(8):1028-38. doi: 10.1158/2326-6066.Cir-22-0088. PubMed PMID: 35726891; PMCID: PMC9357105.
     
  41. Liu JC, Egleston B, Blackman E, Ragin C. Racial Survival Disparities in Head and Neck Cancer Clinical Trials. J Natl Cancer Inst. 2022. Epub 20221207. doi: 10.1093/jnci/djac219. PubMed PMID: 36477855.
     
  42. Longacre ML, Miller MF, Fang CY. The psychometric properties of a caregiving-related strain scale in oncology. Qual Life Res. 2022. Epub 20220902. doi: 10.1007/s11136-022-03235-7. PubMed PMID: 36053408.
     
  43. Luong T, Cukierman E. Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFβ inhibition. BMC Cancer. 2022;22(1):1255. Epub 20221202. doi: 10.1186/s12885-022-10330-y. PubMed PMID: 36461015; PMCID: PMC9719234.
     
  44. Majtan T, Kožich V, Kruger WD. Recent therapeutic approaches to cystathionine beta-synthase-deficient homocystinuria. Br J Pharmacol. 2022. Epub 20221123. doi: 10.1111/bph.15991. PubMed PMID: 36417581.
     
  45. Makhov P, Fazliyeva R, Tufano A, Uzzo RG, Cai KQ, Serebriiskii I, Snyder NW, Andrews AJ, Kolenko VM. Acetyl-CoA Counteracts the Inhibitory Effect of Antiandrogens on Androgen Receptor Signaling in Prostate Cancer Cells. Cancers (Basel). 2022;14(23). Epub 20221129. doi: 10.3390/cancers14235900. PubMed PMID: 36497382; PMCID: PMC9738902.
     
  46. Mani S, Ghosh J, Rhon-Calderon EA, Lan Y, Ord T, Kalliora C, Chan J, Schultz B, Vaughan-Williams E, Coutifaris C, Sapienza C, Senapati S, Bartolomei MS, Mainigi M. Embryo cryopreservation leads to sex-specific DNA methylation perturbations in both human and mouse placentas. Hum Mol Genet. 2022;31(22):3855-72. doi: 10.1093/hmg/ddac138. PubMed PMID: 35717573; PMCID: PMC9652110.
     
  47. Marziliano A, Diefenbach MA, Hudson SV, Tagai EK, Handorf EA, Bator A, Miller SM. Demographic and Psychosocial Characteristics Associated With Use of a Prostate Cancer Survivorship Website: Implications From a Multisite Randomized Controlled Trial. J Med Internet Res. 2022;24(3):e27890. Epub 20220321. doi: 10.2196/27890. PubMed PMID: 35311678; PMCID: PMC8981019.
     
  48. Mizukami T, Bedford JT, Liao S, Greene LH, Roder H. Effects of ionic strength on the folding and stability of SAMP1, a ubiquitin-like halophilic protein. Biophys J. 2022;121(4):552-64. Epub 20220119. doi: 10.1016/j.bpj.2022.01.010. PubMed PMID: 35063455; PMCID: PMC8874027.
     
  49. Mizukami T, Roder H. Advances in Mixer Design and Detection Methods for Kinetics Studies of Macromolecular Folding and Binding on the Microsecond Time Scale. Molecules. 2022;27(11). Epub 20220525. doi: 10.3390/molecules27113392. PubMed PMID: 35684328; PMCID: PMC9182321.
     
  50. Mo X, Kazmi HR, Preston-Alp S, Zhou B, Zaidi MR. Interferon-gamma induces melanogenesis via post-translational regulation of tyrosinase. Pigment Cell Melanoma Res. 2022;35(3):342-55. Epub 20220320. doi: 10.1111/pcmr.13036. PubMed PMID: 35266648; PMCID: PMC9050958.
     
  51. Modi V, Dunbrack RL. Kincore: a web resource for structural classification of protein kinases and their inhibitors. Nucleic Acids Res. 2022;50(D1):D654-d64. doi: 10.1093/nar/gkab920. PubMed PMID: 34643709; PMCID: PMC8728253.
     
  52. Mughal TI, Pemmaraju N, Bejar R, Gale RP, Bose P, Kiladjian JJ, Prchal J, Royston D, Pollyea D, Valent P, Brümmendorf TH, Skorski T, Patnaik M, Santini V, Fenaux P, Kucine N, Verstovsek S, Mesa R, Barbui T, Saglio G, Van Etten RA. Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies. Hematol Oncol. 2022;40(4):491-504. Epub 20220415. doi: 10.1002/hon.2987. PubMed PMID: 35368098.
     
  53. Murthy SS, Ortiz A, DuBois T, Sorice KA, Nguyen M, Castellanos JA, Pinheiro P, Gonzalez ET, Lynch SM. The effect of social determinants of health on utilization of surgical treatment for hepatocellular carcinoma patients. Am J Surg. 2022. Epub 20221012. doi: 10.1016/j.amjsurg.2022.10.011. PubMed PMID: 36344305.
     
  54. Nguyen TT, Silva FN, Golemis EA. Aurora Kinases as Therapeutic Targets in Head and Neck Cancer. Cancer J. 2022;28(5):387-400. doi: 10.1097/ppo.0000000000000614. PubMed PMID: 36165728.
     
  55. Osmanbeyoglu HU, Palmer D, Sagan A, Sementino E, Becich MJ, Testa JR. Isolated BAP1 Genomic Alteration in Malignant Pleural Mesothelioma Predicts Distinct Immunogenicity with Implications for Immunotherapeutic Response. Cancers (Basel). 2022;14(22). Epub 20221116. doi: 10.3390/cancers14225626. PubMed PMID: 36428720; PMCID: PMC9688367.
     
  56. Parker MI, Meyer JE, Golemis EA, Dunbrack RL. Delineating the RAS Conformational Landscape. Cancer Res. 2022;82(13):2485-98. doi: 10.1158/0008-5472.Can-22-0804. PubMed PMID: 35536216; PMCID: PMC9256797.
     
  57. Patel K, Murray MG, Whelan KA. Roles for GADD45 in Development and Cancer. Adv Exp Med Biol. 2022;1360:23-39. doi: 10.1007/978-3-030-94804-7_2. PubMed PMID: 35505160.
     
  58. Pirestani S, Golemis EA. H2-gamendazole: a new therapeutic lead for the treatment of polycystic kidney disease. Am J Physiol Renal Physiol. 2022;323(6):F613-f5. Epub 20220915. doi: 10.1152/ajprenal.00225.2022. PubMed PMID: 36108051; PMCID: PMC9705014.
     
  59. Raghavan KS, Francescone R, Franco-Barraza J, Gardiner JC, Vendramini-Costa DB, Luong T, Pourmandi N, Andren A, Kurimchak A, Ogier C, Campbell PM, Duncan JS, Lyssiotis CA, Languino LR, Cukierman E. NetrinG1(+) cancer-associated fibroblasts generate unique extracellular vesicles that support the survival of pancreatic cancer cells under nutritional stress. Cancer Res Commun. 2022;2(9):1017-36. Epub 20220919. doi: 10.1158/2767-9764.crc-21-0147. PubMed PMID: 36310768; PMCID: PMC9608356.
     
  60. Rodriguez CP, Kang H, Geiger JL, Burtness B, Chung CH, Pickering CR, Fakhry C, Le QT, Yom SS, Galloway TJ, Golemis E, Li A, Shoop J, Wong S, Mehra R, Skinner H, Saba NF, Flores ER, Myers JN, Ford JM, Karchin R, Ferris RL, Kunos C, Lynn JM, Malik S. Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma. J Natl Cancer Inst. 2022;114(12):1619-27. doi: 10.1093/jnci/djac163. PubMed PMID: 36053203; PMCID: PMC9745425.
     
  61. Sementino E, Kadariya Y, Cheung M, Menges CW, Tan Y, Kukuyan AM, Shrestha U, Karchugina S, Cai KQ, Peri S, Duncan JS, Chernoff J, Testa JR. Inactivation of p21-Activated Kinase 2 (Pak2) Inhibits the Development of Nf2-Deficient Tumors by Restricting Downstream Hedgehog and Wnt Signaling. Mol Cancer Res. 2022;20(5):699-711. doi: 10.1158/1541-7786.Mcr-21-0837. PubMed PMID: 35082167; PMCID: PMC9081258.
     
  62. Serebriiskii IG, Pavlov V, Tricarico R, Andrianov G, Nicolas E, Parker MI, Newberg J, Frampton G, Meyer JE, Golemis EA. Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers. Nat Commun. 2022;13(1):1618. Epub 20220325. doi: 10.1038/s41467-022-29227-2. PubMed PMID: 35338148; PMCID: PMC8956741.
     
  63. Sertori R, Lin JX, Martinez E, Rana S, Sharo A, Kazemian M, Sunderam U, Andrake M, Shinton S, Truong B, Dunbrack RM, Liu C, Srinivasan R, Brenner SE, Seroogy CM, Puck JM, Leonard WJ, Wiest DL. Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency. Front Immunol. 2022;13:928252. Epub 20220729. doi: 10.3389/fimmu.2022.928252. PubMed PMID: 35967429; PMCID: PMC9372720.
     
  64. Shah SM, Demidova EV, Lesh RW, Hall MJ, Daly MB, Meyer JE, Edelman MJ, Arora S. Therapeutic implications of germline vulnerabilities in DNA repair for precision oncology. Cancer Treat Rev. 2022;104:102337. Epub 20220105. doi: 10.1016/j.ctrv.2021.102337. PubMed PMID: 35051883; PMCID: PMC9016579.
     
  65. Shrestha J, Santerre M, Allen CNS, Arjona SP, Merali C, Mukerjee R, Chitrala KN, Park J, Bagashev A, Bui V, Eugenin EA, Merali S, Kaul M, Chin J, Sawaya BE. HIV-1 gp120 Impairs Spatial Memory Through Cyclic AMP Response Element-Binding Protein. Front Aging Neurosci. 2022;14:811481. Epub 20220509. doi: 10.3389/fnagi.2022.811481. PubMed PMID: 35615594; PMCID: PMC9124804.
     
  66. Singh T, Beatty A, Peterson JR. The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells. Cell Death Discov. 2022;8(1):253. Epub 20220506. doi: 10.1038/s41420-022-01044-y. PubMed PMID: 35523770; PMCID: PMC9076840.
     
  67. Sivkina AL, Karlova MG, Valieva ME, McCullough LL, Formosa T, Shaytan AK, Feofanov AV, Kirpichnikov MP, Sokolova OS, Studitsky VM. Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT. Commun Biol. 2022;5(1):2. Epub 20220110. doi: 10.1038/s42003-021-02948-8. PubMed PMID: 35013515; PMCID: PMC8748794.
     
  68. Sorice KA, Fang CY, Wiese D, Ortiz A, Chen Y, Henry KA, Lynch SM. Systematic review of neighborhood socioeconomic indices studied across the cancer control continuum. Cancer Med. 2022;11(10):2125-44. Epub 20220214. doi: 10.1002/cam4.4601. PubMed PMID: 35166051; PMCID: PMC9119356.
     
  69. Sultan FA, Sawaya BE. Gadd45 in Neuronal Development, Function, and Injury. Adv Exp Med Biol. 2022;1360:117-48. doi: 10.1007/978-3-030-94804-7_9. PubMed PMID: 35505167.
     
  70. Swatler J, Turos-Korgul L, Brewinska-Olchowik M, De Biasi S, Dudka W, Le BV, Kominek A, Cyranowski S, Pilanc P, Mohammadi E, Cysewski D, Kozlowska E, Grabowska-Pyrzewicz W, Wojda U, Basak G, Mieczkowski J, Skorski T, Cossarizza A, Piwocka K. 4-1BBL-containing leukemic extracellular vesicles promote immunosuppressive effector regulatory T cells. Blood Adv. 2022;6(6):1879-94. doi: 10.1182/bloodadvances.2021006195. PubMed PMID: 35130345; PMCID: PMC8941461.
     
  71. Tang B, Lee HO, Gupta S, Wang L, Kurimchak AM, Duncan JS, Kruger WD. Extracellular 5'-methylthioadenosine inhibits intracellular symmetric dimethylarginine protein methylation of FUSE-binding proteins. J Biol Chem. 2022;298(9):102367. Epub 20220811. doi: 10.1016/j.jbc.2022.102367. PubMed PMID: 35963436; PMCID: PMC9467882.
     
  72. Topchu I, Pangeni RP, Bychkov I, Miller SA, Izumchenko E, Yu J, Golemis E, Karanicolas J, Boumber Y. The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors. Cell Mol Life Sci. 2022;79(6):285. Epub 20220509. doi: 10.1007/s00018-022-04321-2. PubMed PMID: 35532818; PMCID: PMC9520630.
     
  73. Torres-Ayuso P, Brognard J. Degraders: The Ultimate Weapon Against Amplified Driver Kinases in Cancer. Mol Pharmacol. 2022;101(4):191-200. Epub 20220203. doi: 10.1124/molpharm.121.000306. PubMed PMID: 35115411; PMCID: PMC9092480.
     
  74. van Wijnen AJ, Golemis E, Hanukoglu I, Tsui SK, Hu E, Ul-Hasan S, Joy J, Su AI, Tsueng G. A retrospective evaluation of a decade of Gene Wiki Reviews and their impact. Gene. 2022;830:146534. Epub 20220504. doi: 10.1016/j.gene.2022.146534. PubMed PMID: 35525475.
     
  75. Vekariya U, Toma MM, Nieborowska-Skorska M, Le BV, Caron MC, Kukuyan AM, Sullivan-Reed K, Podszywalow-Bartnicka P, Chitrala KN, Atkins J, Drzewiecka M, Feng W, Chan J, Chatla S, Golovine K, Jelinek J, Sliwinski T, Ghosh J, Matlawska-Wasowska K, Chandramouly G, Nejati R, Wasik MA, Sykes S, Piwocka K, Hadzijusufovic E, Valent P, Pomerantz RT, Morton G, Childers W, Zhao H, Paietta E, Levine RL, Tallman MS, Fernandez H, Litzow MR, Gupta G, Masson JY, Skorski T. DNA polymerase theta protects leukemia cells from metabolic-induced DNA damage. Blood. 2022. Epub 20221229. doi: 10.1182/blood.2022018428. PubMed PMID: 36580665.
     
  76. Whitaker AM, Stark WJ, Freudenthal BD. Processing oxidatively damaged bases at DNA strand breaks by APE1. Nucleic Acids Res. 2022;50(16):9521-33. doi: 10.1093/nar/gkac695. PubMed PMID: 36018803; PMCID: PMC9458457.
     
  77. Xu Q, Dunbrack RL. The protein common assembly database (ProtCAD)-a comprehensive structural resource of protein complexes. Nucleic Acids Res. 2022. Epub 20221027. doi: 10.1093/nar/gkac937. PubMed PMID: 36300618.
     
  78. Zaidi MR, Liebermann DA. Gadd45 in Senescence. Adv Exp Med Biol. 2022;1360:109-16. doi: 10.1007/978-3-030-94804-7_8. PubMed PMID: 35505166.
     
  79. Zhang T, Yin C, Fedorov A, Qiao L, Bao H, Beknazarov N, Wang S, Gautam A, Williams RM, Crawford JC, Peri S, Studitsky V, Beg AA, Thomas PG, Walkley C, Xu Y, Poptsova M, Herbert A, Balachandran S. ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis. Nature. 2022;606(7914):594-602. Epub 20220525. doi: 10.1038/s41586-022-04753-7. PubMed PMID: 35614224; PMCID: PMC9373927.
     
  80. Zhang Y, Truong B, Fahl SP, Martinez E, Cai KQ, Al-Saleem ED, Gong Y, Liebermann DA, Soboloff J, Dunbrack R, Levine RL, Fletcher S, Kappes D, Sykes SM, Shapiro P, Wiest DL. The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm. Blood. 2022;140(4):359-73. doi: 10.1182/blood.2021013068. PubMed PMID: 35436326; PMCID: PMC9335498.
     
  81. Zhou B, Basu J, Kazmi HR, Chitrala KN, Mo X, Preston-Alp S, Cai KQ, Kappes D, Zaidi MR. Interferon-gamma signaling promotes melanoma progression and metastasis. Oncogene. 2022. Epub 20221203. doi: 10.1038/s41388-022-02561-x. PubMed PMID: 36463370.
     
  82. Zimmaro LA, Sorice KA, Handorf EA, Daly MB, Reese JB. Understanding clinical communication about mood disturbance symptoms among breast cancer patients: A mixed methods analysis. Patient Educ Couns. 2022;105(7):2089-95. Epub 20220210. doi: 10.1016/j.pec.2022.02.004. PubMed PMID: 35184908; PMCID: PMC9203906.

2021

  1. Basu J, Reis BS, Peri S, Zha J, Hua X, Ge L, Ferchen K, Nicolas E, Czyzewicz P, Cai KQ, Tan Y, Fuxman Bass JI, Walhout AJM, Grimes HL, Grivennikov SI, Mucida D, Kappes DJ. Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4(+) T cell identity and function. Nat Immunol. 2021;22(8):969-82. Epub 2021/07/28. doi: 10.1038/s41590-021-00980-8. PubMed PMID: 34312548.
     
  2. Beatty A, Singh T, Tyurina YY, Tyurin VA, Samovich S, Nicolas E, Maslar K, Zhou Y, Cai KQ, Tan Y, Doll S, Conrad M, Subramanian A, Bayır H, Kagan VE, Rennefahrt U, Peterson JR. Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1. Nat Commun. 2021;12(1):2244. Epub 2021/04/16. doi: 10.1038/s41467-021-22471-y. PubMed PMID: 33854057; PMCID: PMC8046803
     
  3. Campbell KS. Mystery Checkpoint Revealed: KIR3DL3 Finally Found a Ligand in HHLA2. Cancer Immunol Res. 2021;9(2):128. Epub 2021/02/05. doi: 10.1158/2326-6066.Cir-20-0996. PubMed PMID: 33536266.
     
  4. Cheng S, Nethi SK, Al-Kofahi M, Prabha S. Pharmacokinetic-Pharmacodynamic Modeling of Tumor Targeted Drug Delivery Using Nano-Engineered Mesenchymal Stem Cells. Pharmaceutics. 2021;13(1). Epub 2021/01/16. doi: 10.3390/pharmaceutics13010092. PubMed PMID: 33445681; PMCID: PMC7828117.
     
  5. Cukierman E. A Reflection on How Carcinoma-Associated Fibroblasts Were Recognized as Active Participants of Epithelial Tumorigenesis. Cancer Res. 2021;81(18):4668-70. Epub 2021/09/17. doi: 10.1158/0008-5472.Can-21-2553. PubMed PMID: 34526348.
     
  6. Deneka AY, Kopp MC, Nikonova AS, Gaponova AV, Kiseleva AA, Hensley HH, Flieder DB, Serebriiskii IG, Golemis EA. Nedd9 Restrains Autophagy to Limit Growth of Early Stage Non-Small Cell Lung Cancer. Cancer Res. 2021;81(13):3717-26. Epub 2021/05/20. doi: 10.1158/0008-5472.Can-20-3626. PubMed PMID: 34006524; PMCID: PMC8277748.
     
  7. Di Marcantonio D, Martinez E, Kanefsky JS, Huhn JM, Gabbasov R, Gupta A, Krais JJ, Peri S, Tan Y, Skorski T, Dorrance A, Garzon R, Goldman AR, Tang HY, Johnson N, Sykes SM. ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia. Mol Cell. 2021;81(13):2752-64.e6. Epub 2021/06/04. doi: 10.1016/j.molcel.2021.05.008. PubMed PMID: 34081901; PMCID: PMC8452149.
     
  8. Duy C, Li M, Teater M, Meydan C, Garrett-Bakelman FE, Lee TC, Chin CR, Durmaz C, Kawabata KC, Dhimolea E, Mitsiades CS, Doehner H, D'Andrea RJ, Becker MW, Paietta EM, Mason CE, Carroll M, Melnick AM. Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence. Cancer Discov. 2021;11(6):1542-61. Epub 2021/01/28. doi: 10.1158/2159-8290.Cd-20-1375. PubMed PMID: 33500244; PMCID: PMC8178167.
     
  9. Fahl SP, Contreras AV, Verma A, Qiu X, Harly C, Radtke F, Zúñiga-Pflücker JC, Murre C, Xue HH, Sen JM, Wiest DL. The E protein-TCF1 axis controls γδ T cell development and effector fate. Cell Rep. 2021;34(5):108716. Epub 2021/02/04. doi: 10.1016/j.celrep.2021.108716. PubMed PMID: 33535043; PMCID: PMC7919611.
     
  10. Fan Q, Gong T, Zheng C, Ng JMY, Chen J, Myers C, Hensley H, Curran T, Yang ZJ. Statins repress hedgehog signaling in medulloblastoma with no bone toxicities. Oncogene. 2021;40(12):2258-72. Epub 2021/03/03. doi: 10.1038/s41388-021-01701-z. PubMed PMID: 33649536.
     
  11. Fang CY, Frosch ZAK. Understanding and Addressing Cancer Care Costs in the United States. JAMA Netw Open. 2021;4(10):e2127964. Epub 2021/10/07. doi: 10.1001/jamanetworkopen.2021.27964. PubMed PMID: 34613407.
     
  12. Fowle H, Zhao Z, Xu Q, Wasserman JS, Wang X, Adeyemi M, Feiser F, Kurimchak AN, Atar D, McEwan BC, Kettenbach AN, Page R, Peti W, Dunbrack RL, Graña X. PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107. Elife. 2021;10. Epub 2021/10/19. doi: 10.7554/eLife.63181. PubMed PMID: 34661528; PMCID: PMC8575462.
     
  13. Francescone R, Barbosa Vendramini-Costa D, Franco-Barraza J, Wagner J, Muir A, Lau AN, Gabitova L, Pazina T, Gupta S, Luong T, Rollins D, Malik R, Thapa RJ, Restifo D, Zhou Y, Cai KQ, Hensley HH, Tan Y, Kruger WD, Devarajan K, Balachandran S, Klein-Szanto AJ, Wang H, El-Deiry WS, Vander Heiden MG, Peri S, Campbell KS, Astsaturov I, Cukierman E. Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression. Cancer Discov. 2021;11(2):446-79. Epub 2020/11/01. doi: 10.1158/2159-8290.Cd-20-0775. PubMed PMID: 33127842; PMCID: PMC7858242.
     
  14. Guo D, Wang Y, Cheng Y, Liao S, Hu J, Du F, Xu G, Liu Y, Cai KQ, Cheung M, Wainwright BJ, Lu QR, Zhao Y, Yang ZJ. Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse. J Exp Med. 2021;218(9). Epub 2021/07/14. doi: 10.1084/jem.20202350. PubMed PMID: 34254999; PMCID: PMC8282281.
     
  15. Harrington N, Chen Y, O'Reilly AM, Fang CY. The role of trust in HPV vaccine uptake among racial and ethnic minorities in the United States: a narrative review. AIMS Public Health. 2021;8(2):352-68. Epub 2021/05/22. doi: 10.3934/publichealth.2021027. PubMed PMID: 34017897; PMCID: PMC8116180.
     
  16. Krais JJ, Wang Y, Patel P, Basu J, Bernhardy AJ, Johnson N. RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage. Nat Commun. 2021;12(1):5016. Epub 2021/08/20. doi: 10.1038/s41467-021-25346-4. PubMed PMID: 34408138; PMCID: PMC8373961.
     
  17. Maifrede S, Le BV, Nieborowska-Skorska M, Golovine K, Sullivan-Reed K, Dunuwille WMB, Nacson J, Hulse M, Keith K, Madzo J, Caruso LB, Gazze Z, Lian Z, Padella A, Chitrala KN, Bartholdy BA, Matlawska-Wasowska K, Di Marcantonio D, Simonetti G, Greiner G, Sykes SM, Valent P, Paietta EM, Tallman MS, Fernandez HF, Litzow MR, Minden MD, Huang J, Martinelli G, Vassiliou GS, Tempera I, Piwocka K, Johnson N, Challen GA, Skorski T. TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors. Cancer Res. 2021;81(19):5089-101. Epub 2021/07/04. doi: 10.1158/0008-5472.Can-20-3761. PubMed PMID: 34215619; PMCID: PMC8487956.
     
  18. Reese JB, Zimmaro LA, Bober SL, Sorice K, Handorf E, Wittenberg E, El-Jawahri A, Beach MC, Wolff AC, Daly MB, Izquierdo B, Lepore SJ. Mobile Technology-Based (mLearning) Intervention to Enhance Breast Cancer Clinicians' Communication About Sexual Health: A Pilot Trial. J Natl Compr Canc Netw. 2021. Epub 2021/08/14. doi: 10.6004/jnccn.2021.7032. PubMed PMID: 34388731; PMCID: PMC8840991.
     
  19. Santerre M, Arjona SP, Allen CN, Callen S, Buch S, Sawaya BE. HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons. Autophagy. 2021;17(7):1768-82. Epub 2021/04/24. doi: 10.1080/15548627.2021.1915641. PubMed PMID: 33890542; PMCID: PMC8354668.
     
  20. Tan Y, Sementino E, Cheung M, Peri S, Menges CW, Kukuyan AM, Zhang T, Khazak V, Fox LA, Ross EA, Ramanathan S, Jhanwar SC, Flores RM, Balachandran S, Testa JR. Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma. Clin Cancer Res. 2021;27(4):1200-13. Epub 2020/11/19. doi: 10.1158/1078-0432.Ccr-18-3683. PubMed PMID: 33203643; PMCID: PMC7887036.
     
  21. Van Rechem C, Ji F, Chakraborty D, Black JC, Sadreyev RI, Whetstine JR. Collective regulation of chromatin modifications predicts replication timing during cell cycle. Cell Rep. 2021;37(1):109799. Epub 2021/10/06. doi: 10.1016/j.celrep.2021.109799. PubMed PMID: 34610305; PMCID: PMC8530517.
     
  22. Wang H, Wei W, Zhang JP, Song Z, Li Y, Xiao W, Liu Y, Zeng MS, Petrus MN, Thomas CJ, Kadin ME, Nakagawa M, Waldmann TA, Yang Y. A novel model of alternative NF-κB pathway activation in anaplastic large cell lymphoma. Leukemia. 2021;35(7):1976-89. Epub 2020/11/14. doi: 10.1038/s41375-020-01088-y. PubMed PMID: 33184494.
     
  23. Ye S, Sharipova D, Kozinova M, Klug L, D'Souza J, Belinsky MG, Johnson KJ, Einarson MB, Devarajan K, Zhou Y, Litwin S, Heinrich MC, DeMatteo R, von Mehren M, Duncan JS, Rink L. Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment. JCI Insight. 2021;6(2). Epub 2020/12/16. doi: 10.1172/jci.insight.143474. PubMed PMID: 33320833; PMCID: PMC7934848.

2020 

  1. Adeshina YO, Deeds EJ, Karanicolas J. Machine learning classification can reduce false positives in structure-based virtual screening. Proc Natl Acad Sci U S A. 2020;117(31):18477-88. Epub 2020/07/17. doi: 10.1073/pnas.2000585117. PubMed PMID: 32669436; PMCID: PMC7414157.
     
  2. Alexander J, Cukierman E. Cancer associated fibroblast: Mediators of tumorigenesis. Matrix Biol. 2020;91-92:19-34. Epub 2020/05/26. doi: 10.1016/j.matbio.2020.05.004. PubMed PMID: 32450219; PMCID: PMC7434664.
     
  3. Cannon AC, Uribe-Alvarez C, Chernoff J. RAC1 as a Therapeutic Target in Malignant Melanoma. Trends Cancer. 2020;6(6):478-88. Epub 2020/05/28. doi: 10.1016/j.trecan.2020.02.021. PubMed PMID: 32460002; PMCID: PMC7380552.
     
  4. Cheng Y, Liao S, Xu G, Hu J, Guo D, Du F, Contreras A, Cai KQ, Peri S, Wang Y, Corney DC, Noronha AM, Chau LQ, Zhou G, Wiest DL, Bellacosa A, Wechsler-Reya RJ, Zhao Y, Yang ZJ. NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma. Cell Rep. 2020;31(12):107782. Epub 2020/06/25. doi: 10.1016/j.celrep.2020.107782. PubMed PMID: 32579914; PMCID: PMC7357167.
     
  5. Clarke TL, Tang R, Chakraborty D, Van Rechem C, Ji F, Mishra S, Ma A, Kaniskan H, Jin J, Lawrence MS, Sadreyev RI, Whetstine JR. Histone Lysine Methylation Dynamics Control EGFR DNA Copy-Number Amplification. Cancer Discov. 2020;10(2):306-25. Epub 2019/11/30. doi: 10.1158/2159-8290.Cd-19-0463. PubMed PMID: 31776131; PMCID: PMC7271978.
     
  6. Deneka AY, Einarson MB, Bennett J, Nikonova AS, Elmekawy M, Zhou Y, Lee JW, Burtness BA, Golemis EA. Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer. Cancers (Basel). 2020;12(2). Epub 2020/02/06. doi: 10.3390/cancers12020306. PubMed PMID: 32012873; PMCID: PMC7072436.
     
  7. Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I. Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell. 2020;38(4):567-83.e11. Epub 2020/09/26. doi: 10.1016/j.ccell.2020.08.015. PubMed PMID: 32976774; PMCID: PMC7572882.
     
  8. Gross S, Mallu P, Joshi H, Schultz B, Go C, Soboloff J. Ca(2+) as a therapeutic target in cancer. Adv Cancer Res. 2020;148:233-317. Epub 2020/07/30. doi: 10.1016/bs.acr.2020.05.003. PubMed PMID: 32723565; PMCID: PMC7412871.
     
  9. Hurtz C, Wertheim GB, Loftus JP, Blumenthal D, Lehman A, Li Y, Bagashev A, Manning B, Cummins KD, Burkhardt JK, Perl AE, Carroll M, Tasian SK. Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL. J Clin Invest. 2020;130(7):3637-53. Epub 2020/03/20. doi: 10.1172/jci134424. PubMed PMID: 32191635; PMCID: PMC7324172.
     
  10. Karakashev S, Fukumoto T, Zhao B, Lin J, Wu S, Fatkhutdinov N, Park PH, Semenova G, Jean S, Cadungog MG, Borowsky ME, Kossenkov AV, Liu Q, Zhang R. EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination Proficient Ovarian Cancers to PARP Inhibition. Cancer Cell. 2020;37(2):157-67.e6. Epub 2020/02/01. doi: 10.1016/j.ccell.2019.12.015. PubMed PMID: 32004442; PMCID: PMC7155421.
     
  11. Khowsathit J, Bazzoli A, Cheng H, Karanicolas J. Computational Design of an Allosteric Antibody Switch by Deletion and Rescue of a Complex Structural Constellation. ACS Cent Sci. 2020;6(3):390-403. Epub 2020/04/02. doi: 10.1021/acscentsci.9b01065. PubMed PMID: 32232139; PMCID: PMC7099597
     
  12. Kiseleva AA, Golemis EA. Informatics-guided drug repurposing for Autosomal Dominant Polycystic Kidney Disease (ADPKD). EBioMedicine. 2020;52:102628. Epub 2020/01/26. doi: 10.1016/j.ebiom.2020.102628. PubMed PMID: 31981981; PMCID: PMC6976921.
     
  13. Krais JJ, Johnson N. BRCA1 Mutations in Cancer: Coordinating Deficiencies in Homologous Recombination with Tumorigenesis. Cancer Res. 2020;80(21):4601-9. Epub 2020/08/05. doi: 10.1158/0008-5472.Can-20-1830. PubMed PMID: 32747362; PMCID: PMC7641968.
     
  14. Krais JJ, Johnson N. Ectopic RNF168 expression promotes break-induced replication-like DNA synthesis at stalled replication forks. Nucleic Acids Res. 2020;48(8):4298-308. Epub 2020/03/18. doi: 10.1093/nar/gkaa154. PubMed PMID: 32182354; PMCID: PMC7192614.
     
  15.  Krais JJ, Wang Y, Bernhardy AJ, Clausen E, Miller JA, Cai KQ, Scott CL, Johnson N. RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers. Cancer Res. 2020;80(13):2848-60. Epub 2020/03/28. doi: 10.1158/0008-5472.Can-19-3033. PubMed PMID: 32213544; PMCID: PMC7335334.
     
  16. Krais JJ, Wang Y, Bernhardy AJ, Clausen E, Miller JA, Cai KQ, Scott CL, Johnson N. RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers. Cancer Res. 2020;80(13):2848-60. Epub 2020/03/28. doi: 10.1158/0008-5472.Can-19-3033. PubMed PMID: 32213544; PMCID: PMC7335334.
     
  17. Kurimchak AM, Herrera-Montávez C, Brown J, Johnson KJ, Sodi V, Srivastava N, Kumar V, Deihimi S, O'Brien S, Peri S, Mantia-Smaldone GM, Jain A, Winters RM, Cai KQ, Chernoff J, Connolly DC, Duncan JS. Functional proteomics interrogation of the kinome identifies MRCKA as a therapeutic target in high-grade serous ovarian carcinoma. Sci Signal. 2020;13(619). Epub 2020/02/20. doi: 10.1126/scisignal.aax8238. PubMed PMID: 32071169; PMCID: PMC7294993.
     
  18. Layek B, Shetty M, Nethi SK, Sehgal D, Starr TK, Prabha S. Mesenchymal Stem Cells As Guideposts for Nanoparticle-Mediated Targeted Drug Delivery in Ovarian Cancer. Cancers (Basel). 2020;12(4). Epub 2020/04/17. doi: 10.3390/cancers12040965. PubMed PMID: 32295145; PMCID: PMC7226169.
     
  19. Le BV, Podszywalow-Bartnicka P, Maifrede S, Sullivan-Reed K, Nieborowska-Skorska M, Golovine K, Yao JC, Nejati R, Cai KQ, Caruso LB, Swatler J, Dabrowski M, Lian Z, Valent P, Paietta EM, Levine RL, Fernandez HF, Tallman MS, Litzow MR, Huang J, Challen GA, Link D, Tempera I, Wasik MA, Piwocka K, Skorski T. TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment. Cell Rep. 2020;33(1):108221. Epub 2020/10/08. doi: 10.1016/j.celrep.2020.108221. PubMed PMID: 33027668; PMCID: PMC7578922.
     
  20. Lynch SM, Sorice K, Tagai EK, Handorf EA. Use of empiric methods to inform prostate cancer health disparities: Comparison of neighborhood-wide association study "hits" in black and white men. Cancer. 2020;126(9):1949-57. Epub 2020/02/06. doi: 10.1002/cncr.32734. PubMed PMID: 32012234; PMCID: PMC7341673.
     
  21. Mookerjee-Basu J, Hooper R, Gross S, Schultz B, Go CK, Samakai E, Ladner J, Nicolas E, Tian Y, Zhou B, Zaidi MR, Tourtellotte W, He S, Zhang Y, Kappes DJ, Soboloff J. Suppression of Ca(2+) signals by EGR4 controls Th1 differentiation and anti-cancer immunity in vivo. EMBO Rep. 2020;21(5):e48904. Epub 2020/03/27. doi: 10.15252/embr.201948904. PubMed PMID: 32212315; PMCID: PMC7202224.
     
  22. Nacson J, Di Marcantonio D, Wang Y, Bernhardy AJ, Clausen E, Hua X, Cai KQ, Martinez E, Feng W, Callén E, Wu W, Gupta GP, Testa JR, Nussenzweig A, Sykes SM, Johnson N. BRCA1 Mutational Complementation Induces Synthetic Viability. Mol Cell. 2020;78(5):951-9.e6. Epub 2020/05/04. doi: 10.1016/j.molcel.2020.04.006. PubMed PMID: 32359443; PMCID: PMC7418109.
     
  23. Shubina M, Tummers B, Boyd DF, Zhang T, Yin C, Gautam A, Guo XJ, Rodriguez DA, Kaiser WJ, Vogel P, Green DR, Thomas PG, Balachandran S. Necroptosis restricts influenza A virus as a stand-alone cell death mechanism. J Exp Med. 2020;217(11). Epub 2020/08/17. doi: 10.1084/jem.20191259. PubMed PMID: 32797196; PMCID: PMC7596817
     
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