Research Interests
Our overall goal is to examine the role of reactions involving thiols and disulfides, and protein disulfide isomerase in hemostasis, atherosclerosis and wound healing. More specifically, to define the role of thiol-disulfide reactions and platelet protein disulfide isomerases in integrin activation and platelet function. A related project is to characterize a transmembrane electron transport system on the platelet surface that reduces disulfide bonds in platelet surface proteins. A final goal is to characterize oxidative modifications of thiols in conditions associated with oxidative stress.
Clinical Interests
- General hematology
- Hemostasis and thrombosis
Education, Training & Credentials
- Fellowship, Oncology, State University of New York Health Science Center at Brooklyn, NY, 1992
- Research Fellowship, Cardeza Center for Hematologic Research, Jefferson Medical College, 1991
- Fellowship, Hematology, Mount Sinai Medical Center, 1989
- Residency, University of Medicine and Dentistry of New Jersey, 1987
- Internship, University of Medicine and Dentistry of New Jersey, 1985
- MD, Rutgers (Robert Wood Johnson) Medical School, 1984
- BS, Rutgers University, 1980
Certifications:
- Internal Medicine
- Hematology
Memberships
- American Society of Hematology
- American Heart Association