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Lewis Katz School of Medicine
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Cardiovascular Surgery

Cardiovascular Surgery

Eros Leotta, MD

Peer -Reviewed Manuscripts: 

  • Levy J, Kashem A, Sunagawa G, Zhao H, Minakata K, Keshavamurthy S, Brann S, Leotta E, Shigemura N, Toyoda Y.  Postoperative Bronchial Complications After Lung Transplantation Related to Anastomosis Suture. Ann Thorac Surg. 2021 Aug 3:S0003-4975(21)01314-X. doi: 10.1016/j.athoracsur.2021.06.077. Online ahead of print.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y.  Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants. Interact Cardiovasc Thorac Surg. 2021 Oct 29;33(5):807-813. doi: 10.1093/icvts/ivab169.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y. Clinical outcomes in patients with end-stage chronic obstructive pulmonary disease: Single versus bilateral lung transplants. Interactive Cardiovascular and Thoracic Surgery. 2021 (In press)
  • Levy J, Kashem MA, Sunagawa, Leotta E, Brann S, Minakata K, Toyoda Y. Post-operative operative bronchial complications following lung transplantation following lung transplantation related to anastomosis suture. Annals of Thoracic Surgery 2021 (In press) 

Abstracts & Presentations: 

  • G. Sunagawa, H. Kehara, M. Kashem, C. Mangukia, S. Brann, E. Leotta, R. Yanagida, K. Minakata, F. Cordova, Y. Toyoda, N. Shigemura. Single Lung Transplant Remains a Viable Alternative to Double Lung Transplantation for the Patients with Severe Secondary Pulmonary Hypertension. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Donor Age, Recipient Age and Transplant Type: How Their Interplay Affects Lung Transplants. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Analysis of Increased Risk Donors Utilized in Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021 
  •  A. S. Bussetty, M. A. Kashem, H. Zhao, G. Sunagawa, E. Leotta, N. Shigemura, R. Yanagida, S. H. Brann, K. Minakata, Y. Toyoda.. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  •  K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Lung Transplantation: Is the Switch to Interrupted Suturing Worth it? The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • S. Mutyala, M. A. Kashem, J. Kanaparthi, N. Shigemura, M. Suryapalam, E. Leotta, G. Sunagawa, K. Minakata, Y. Toyoda. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double-Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  •  E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Study of Donor Age & Lung Transplant Type in Idiopathic Pulmonary Fibrosis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • H.,Kehara, R.Yanagida, A Kashem, C Mangukia, G Sunagawa, S. Brann, E. Leotta, R. Boova, N. Shigemura, K. Minakata, Y. Toyoda.  Outcomes after Lung Re-Transplantation:  A Single-Center Experience. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. Tran, M. Kashem, J. Kanaparthi, H. Zhao, S. Brann, E. Leotta, K. Minakata, R. Yanagida, G. Sunagawa, N. Shigemura, Y. Toyoda. Lung Transplant Survival Regarding Past and Concomitant Cardiac Revascularization. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • Kelly Montgomery, Mohammed A. Kashem, Huaquing Zhao, Norihisa Shigemura, Gengo Sunagawa, Eros H. Leotta, Roh Yanagida, Stacey Brann, Yoshiya Toyoda. Is the Switch to Interrupted Suturing Technique Worth It? The 16th Annual Meeting (Virtual) of Academic Surgical Congress, Feb 2-4, 2021.
  • Bussetty AS, Kashem MA, Kanaparthi J, Zhao H, Sunagawa G, Leotta E, Shigemura N, Yanagida R, Brann SH, Minakata K, Toyoda Y. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 57th Annual Meeting of Society of Thoracic Surgery (virtual), January 29-31, 2021.
  • Tran T, Kashem MA, Kanaparthi J, Zhao H, Brann S, Leotta E, Minakata K, Yanagida R, Sunagawa G, Shigemura N, Toyoda Y. Lung Transplant Survival with Past and Concomitant Cardiac Revascularization. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • M. Suryapalam, M.A. Kashem, G. Sunagawa, S. Brann, E. Leotta, N. Shigemura, Y. Toyoda. A Modern Large-scale Analysis of Heart Transplantation in Elderly Patients. American Heart Association, BCVS Meeting, 2020. Abstract 529. Circulation Research. 2020; 127; Suppl_1
  • Kanaparthi J, Kashem M, Suryapalam M, Toyoda Y. Despite prior results, heart transplant recipients over 70 have worse survival outcomes based on the 2019 united network for organ sharing database. Circulation 2020;142: A16930. American Heart Association Scientific Sessions 2020. Nov 17, 2020.
  • Y. Toyoda, A. Kashem, G. Sunagawa, S. Brann, K. Minakata, E. Leotta, N. Shigemura.  Survival Outcome of Single and Double Lung Transplantation in End-Stage COPD Patients. Virtual Room 115, 10:18 am. Lung Transplant and Basic Session, Oct-9, 2020. The 34th Annual Meeting of the European Association of Cardio-Thoracic Surgery. Barcelona, Spain (Virtual), October 8-11, 2020.
  •  Kashem MA. Suryapalam M, Sunagawa G, Brann S, Minakata K, Leotta E, Shigemura N, Toyoda Y. Older Donor Lungs: Are They Viable Options Now for Organ Transplantation? American College of Surgery. Clinical Congress (Virtual)- ID 2158. October 3-7, 2020.
  • Kanaparthi, J., Kashem, M. A., Suryapalam, M., Zhao, H., Brann, S., Leotta, E., Minakata, K., Keshavamurthy, S., Shigemura, N., & Toyoda, Y. (2020). Prior and Perioperative Revascularization Does Not Affect Survival in Lung Transplant Patients. The Annals of thoracic surgery, 109(6), 1677–1683. https://doi.org/10.1016/j.athoracsur.2020.01.016
  • Impact of Donor Age on IPF Patient Survival in Lung Transplantation S Dutta, A Kashem, G Sunagawa, S Brann, E Leotta, N Shigemura,Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S387, 2020. https://doi.org/10.1016/j.healun.2020.01.503
  • Do Public Health Service Increased Risk Donor Lungs Negatively Affect Survival Outcomes? J Lasky, A Kashem, SH Brann, E Leotta, S Gengo, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S382, 2020 https://doi.org/10.1016/j.healun.2020.01.489
  • Comparing the Use of Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass in Lung Transplantation P Ortiz, M Kashem, G Sunagawa, E Leotta, K Minakata, S Brann, N.Shigemura, Y.Toyoda The Journal of Heart and Lung Transplantation 39 (4), S104, 2020 https://doi.org/10.1016/j.healun.2020.01.962
  • Patients over 70 Years Old Show Acceptable Outcomes after Undergoing Concomitant Coronary Artery Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, S Brann, N Shigemura, E. Leotta, Y. ToyodaThe Journal of Heart and Lung Transplantation 39 (4), S370-S371 , 2020 https://doi.org/10.1016/j.healun.2020.01.462
  • Younger Patients Show Acceptable Outcomes after Undergoing Concomitant Coronary Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, N Shigemura, S Brann, E. Leotta, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S370, 2020 https://doi.org/10.1016/j.healun.2020.01.461
  • Assessing Lung Transplant Survival Following Donation after Cardiac Death: A Single Center Experience J Lasky, A Kashem, SH Brann, G Sunagawa, E Leotta, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S381, 2020 https://doi.org/10.1016/j.healun.2020.01.487
  • Wait or No Wait for Reducing Body Weight before Lung Transplant N Guynn, A Kashem, SH Brann, K Minakata, G Sunagawa, E Leotta, N Shigemura, Y Toyoda The Journal of Heart and Lung Transplantation 39 (4), S317-S318, 2020 https://doi.org/10.1016/j.healun.2020.01.716

Suyog Mokashi, MD

Peer-Reviewed Manuscripts: 

  • Chauhan D, Orlandi V, Rajab TK, Bedeir K, Volfovsky A, Mokashi S.  Postoperative Outcomes in Infants Undergoing ABO-incompatible Heart Transplantation in the United States.  Ann Thorac Surg. 2021 Sep 25:S0003-4975(21)01645-3. doi: 10.1016/j.athoracsur.2021.08.039. Online ahead of print.

Norihisa Shigemura, MD

Peer-Reviewed Manuscripts: 

  • Hayanga JWA, Shigemura N, Sanchez P. Commentary: Dispensing with compliance.  J Thorac Cardiovasc Surg. 2021 Jun;161(6):1976-1977. doi: 10.1016/j.jtcvs.2020.07.082. Epub 2020 Aug 3.
  • Suryapalam M, Kashem M, Zhao H, Shigemura N, Toyoda Y, Keshavamurthy S. An Anthropometric Study of Lung Donors. Prog Transplant. 2021 Sep;31(3):211-218. doi: 10.1177/15269248211024611. Epub 2021 Jul 22.
  • Mangukia C, Shigemura N, Stacey B, Sunagawa G, Muhammad N, Espinosa J, Kehara H, Yanagida R, Kashem MA, Minakata K, Toyoda Y. Donor quality assessment and size match in lung transplantation. Indian J Thorac Cardiovasc Surg. 2021 Sep;37(Suppl 3):401-415. doi: 10.1007/s12055-021-01251-9. Epub 2021 Sep 15.
  • Shigemura N, Cordova F, Hayanga AJ, Criner G, Toyoda Y.  Lung transplantation and coronavirus disease 2019 (COVID-19): a roadmap for the enduring pandemic. J Thorac Dis. 2021 Dec;13(12):6755-6759. doi: 10.21037/jtd-21-1667.
  • Levy J, Kashem A, Sunagawa G, Zhao H, Minakata K, Keshavamurthy S, Brann S, Leotta E, Shigemura N, Toyoda Y.  Postoperative Bronchial Complications After Lung Transplantation Related to Anastomosis Suture. Ann Thorac Surg. 2021 Aug 3:S0003-4975(21)01314-X. doi: 10.1016/j.athoracsur.2021.06.077. Online ahead of print.
  • Zheng M, Yousef I, Mamary AJ, Zhao H, McEldrew J, Adika A, Shigemura N, Cordova F, Criner GJ, Mulhall P, Galli J, Shenoy K, Brown J, Marchetti N, Rali P, Sehgal S.  Venous thromboembolism in lung transplant recipients real world experience from a high volume center.  J Heart Lung Transplant. 2021 Oct;40(10):1145-1152. doi: 10.1016/j.healun.2021.07.010. Epub 2021 Jul 22.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y.  Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants. Interact Cardiovasc Thorac Surg. 2021 Oct 29;33(5):807-813. doi: 10.1093/icvts/ivab169.
  • Timofeeva OA, Choe J, Alsammak M, Yoon EJ, Geier SS, Mathew L, McCollick A, Carney K, Au J, Diamond A, Galli JA, Shenoy K, Mamary A, Sehgal S, Mulhall P, Toyoda Y, Shigemura N, Cordova F, Criner G, Brown JC.  Guiding therapeutic plasma exchange for antibody-mediated rejection treatment in lung transplant recipients - a retrospective study. Transpl Int. 2021 Apr;34(4):700-708. doi: 10.1111/tri.13825. Epub 2021 Feb 26
  • Ander EH, Kashem A, Zhao H, Montgomery K, Sunagawa G, Yanagida R, Shigemura N, Toyoda Y.  Lung Transplant Type and Donor Age in Idiopathic Pulmonary Fibrosis: A Single Center Study. J Surg Res. 2022 Mar;271:125-136. doi: 10.1016/j.jss.2021.10.027. Epub 2021 Dec 11.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y. Clinical outcomes in patients with end-stage chronic obstructive pulmonary disease: Single versus bilateral lung transplants. Interactive Cardiovascular and Thoracic Surgery. 2021 (In press)
  • Shigemura N, Cordova F, Criner G, Toyoda Y. Current Precautions and Future Directions in Lung Transplantation during the COVID-19 Pandemic. Transpl Int. 2020 Jul 3
  • Kanaparthi J, Kashem MA, Suryapalam M, Zhao H, Brann S, Leotta E, Minakata K, Keshavamurthy S, Shigemura N, Toyoda Y. Prior and Perioperative Revascularization Does Not Affect Survival in Lung Transplant Patients. Ann Thorac Surg. 2020;109:1677-1683.
  • Tane S, Noda K, Toyoda Y, Shigemura N. Bronchial-arterial-circulation-sparing lung preservation: A new organ protection approach for lung transplantation. Transplantation. 2020;104:490-499.
  • Shigemura N, Toyoda Y. Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation. Transpl Int. 2020;33:347-355.

Abstracts and Presentations: 

  • C. Mangukia, A. Kashem, J. Levy, N. Shigemura, Y. Toyoda. Splitting the Lungs in a Box for Single Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • G. Sunagawa, H. Kehara, M. Kashem, C. Mangukia, S. Brann, E. Leotta, R. Yanagida, K. Minakata, F. Cordova, Y. Toyoda, N. Shigemura. Single Lung Transplant Remains a Viable Alternative to Double Lung Transplantation for the Patients with Severe Secondary Pulmonary Hypertension. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Donor Age, Recipient Age and Transplant Type: How Their Interplay Affects Lung Transplants. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Analysis of Increased Risk Donors Utilized in Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021 
  •  A. S. Bussetty, M. A. Kashem, H. Zhao, G. Sunagawa, E. Leotta, N. Shigemura, R. Yanagida, S. H. Brann, K. Minakata, Y. Toyoda.. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Lung Transplantation: Is the Switch to Interrupted Suturing Worth it? The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • S. Mutyala, T. Tran, M. A. Kashem, H. Zhao, N. Shigemura, Y. Toyoda. Single Lung Transplantation in Patients under 50: Single Center and UNOS Analysis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • S. Mutyala, M. A. Kashem, J. Kanaparthi, N. Shigemura, M. Suryapalam, E. Leotta, G. Sunagawa, K. Minakata, Y. Toyoda. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double-Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Study of Donor Age & Lung Transplant Type in Idiopathic Pulmonary Fibrosis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • H. Kehara, R. Yanagida, A. Kashem, C. Mangukia, G. Sunagawa, S. Brann, E. Leotta, R. Boova, N. Shigemura, K. Minakata, Y. Toyoda. Outcomes after Lung Re-Transplantation: A Single-Center Experience. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • A. Bussetty, S. Mutyala, K. Montgomery, M. A. Kashem, H. Zhao, N. Shigemura, Y. Toyoda. A Single-Center Analysis of Survival Outcome between Donor after Cardiac Death and Donor after Brain Death. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. N. Tran, M. Kashem, H. Zhao, G. Sunagawa, N. Shigemura, R. Yanagida, H. Kehara, Y. Toyoda. Survival Outcomes of Redo Lung Transplantation: UNOS Database. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. Tran, M. Kashem, J. Kanaparthi, H. Zhao, S. Brann, E. Leotta, K. Minakata, R. Yanagida, G. Sunagawa, N. Shigemura, Y. Toyoda. Lung Transplant Survival Regarding Past and Concomitant Cardiac Revascularization. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • M. Suryapalam, M. Kashem, N. Shigemura, Y. Toyoda. Combined Heart-Lung Transplantation: UNOS Data Analysis for Long-Term Survival Outcome. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  •  A. Firoz, M. A. Kashem, S. Jafar, N. Shigemura, Y. Toyoda. Survival Outcome of Combined Heart and Lung Transplantation: Single Center vs. UNOS Data. Control/Tracking Number: 21-A-3944-ISHLT.  The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • Kelly Montgomery, Mohammed A. Kashem, Huaquing Zhao, Norihisa Shigemura, Gengo Sunagawa, Eros H. Leotta, Roh Yanagida, Stacey Brann, Yoshiya Toyoda. Is the Switch to Interrupted Suturing Technique Worth It? The 16th Annual Meeting (Virtual) of Academic Surgical Congress, Feb 2-4, 2021.
  • Bussetty AS, Kashem MA, Kanaparthi J, Zhao H, Sunagawa G, Leotta E, Shigemura N, Yanagida R, Brann SH, Minakata K, Toyoda Y. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 57th Annual Meeting of Society of Thoracic Surgery (virtual), January 29-31, 2021.
  • Mutyala K, Kanaparthi J, Kashem MA, Shigemura N, Toyoda Y. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • Tran T, Kashem MA, Zhao H, Shigemura N, Toyoda Y. Redo-Lung Transplantation Survival Outcomes from UNOS Database. Abstract Number: 923789. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • Tran T, Kashem MA, Kanaparthi J, Zhao H, Brann S, Leotta E, Minakata K, Yanagida R, Sunagawa G, Shigemura N, Toyoda Y. Lung Transplant Survival with Past and Concomitant Cardiac Revascularization. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • M. Suryapalam, M.A. Kashem, G. Sunagawa, S. Brann, E. Leotta, N. Shigemura, Y. Toyoda. A Modern Large-scale Analysis of Heart Transplantation in Elderly Patients. American Heart Association, BCVS Meeting, 2020. Abstract 529. Circulation Research. 2020; 127; Suppl_1
  •  Y. Toyoda, A. Kashem, G. Sunagawa, S. Brann, K. Minakata, E. Leotta, N. Shigemura.  Survival Outcome of Single and Double Lung Transplantation in End-Stage COPD Patients. Virtual Room 115, 10:18 am. Lung Transplant and Basic Session, Oct-9, 2020. The 34th Annual Meeting of the European Association of Cardio-Thoracic Surgery. Barcelona, Spain (Virtual), October 8-11, 2020.
  •  Kashem MA. Suryapalam M, Sunagawa G, Brann S, Minakata K, Leotta E, Shigemura N, Toyoda Y. Older Donor Lungs: Are They Viable Options Now for Organ Transplantation? American College of Surgery. Clinical Congress (Virtual)- ID 2158. October 3-7, 2020.
  • P. Ortiz, M. A. Kashem, G. Sunagawa, E. Leotta, S. Brann, N. Shigemura, Y. Toyoda. Double and Single Lung Transplantation in Elderly Patients. The 15th Academic Surgical Congress. February 4-5, 2020. Orlando, FL
  • R. Boova, M. Kashem, D. DeFazio, C. McAndrew, K. Minakata, N. Shigemura, B. Moser, Y. Toyoda. Preoperative MDCT Is Not An Accurate Predictor of Implant Size For Surgical Aortic Valve Replacement. The 15th Academic Surgical Congress. February 4-5, 2020. Orlando, FL 
  • Shigemura N*, Cordova F, Criner G, Toyoda Y. Current precautions and future directions in lung transplantation during the COVID-19 pandemic. Transplant Int. 2020. [Epub ahead of print]  PMID:  (Shigemura,N. Corresponding Author)
  • Shigemura, N., & Hsin, M. K. (2019). Commentary: A positively out-of-body experience for lungs. The Journal of thoracic and cardiovascular surgery, S0022-5223(19)31605-8. Advance online publication. https://doi.org/10.1016/j.jtcvs.2019.07.070
  • Joubert, K. D., Awori Hayanga, J., Strollo, D. C., Lendermon, E. A., Yousem, S. A., Luketich, J. D., Ensor, C. R., & Shigemura, N. (2019). Outcomes after lung transplantation for patients with occupational lung diseases. Clinical transplantation, 33(1), e13460. https://doi.org/10.1111/ctr.13460
  • Hayanga, J., Hayanga, H. K., Holmes, S. D., Ren, Y., Shigemura, N., Badhwar, V., & Abbas, G. (2019). Mechanical ventilation and extracorporeal membrane oxygenation as a bridge to lung transplantation: Closing the gap. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 38(10), 1104–1111. https://doi.org/10.1016/j.healun.2019.06.026
  • Naito, N., Cook, K., Toyoda, Y., & Shigemura, N. (2018). Artificial Lungs for Lung Failure: JACC Technology Corner. Journal of the American College of Cardiology, 72(14), 1640–1652. https://doi.org/10.1016/j.jacc.2018.07.049
  • Shigemura N. (2018). Extracorporeal lung support for advanced lung failure: a new era in thoracic surgery and translational science. General thoracic and cardiovascular surgery, 66(3), 130–136. https://doi.org/10.1007/s11748-017-0880-z
  • Shigemura, N., Tane, S., & Noda, K. (2018). The Bronchial Arterial Circulation in Lung Transplantation: Bedside to Bench to Bedside, and Beyond. Transplantation, 102(8), 1240–1249. https://doi.org/10.1097/TP.0000000000002180
  • Shigemura N. (2019). Lung transplantation and beyond: continued challenges in the wake of significant progress. Journal of thoracic disease, 11(Suppl 3), S413–S416. https://doi.org/10.21037/jtd.2018.11.112
  • Xie, M., Lee, J., Crespo, M., Fajt, M. L., Shigemura, N., Pilewski, J. M., & Petrov, A. A. (2019). Successful Lung Transplantation in a Patient with Chronic Granulomatous Disease. Journal of clinical immunology, 39(4), 347–349. https://doi.org/10.1007/s10875-019-00623-6
  • Shigemura N. (2019). Primary graft dysfunction and beyond after lung transplantation in the current era. Transplant international : official journal of the European Society for Organ Transplantation, 32(3), 241–243. https://doi.org/10.1111/tri.13385
  • Ensor, C. R., Iasella, C. J., Harrigan, K. M., Morrell, M. R., Moore, C. A., Shigemura, N., Zeevi, A., McDyer, J. F., & Venkataramanan, R. (2018). Increasing tacrolimus time-in-therapeutic range is associated with superior one-year outcomes in lung transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 18(6), 1527–1533. https://doi.org/10.1111/ajt.14723
  • Shigemura, N., & Toyoda, Y. (2020). Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation. Transplant international : official journal of the European Society for Organ Transplantation, 33(4), 347–355. https://doi.org/10.1111/tri.13533
  • Shah, P. R., Boisen, M. L., Winger, D. G., Marquez, J., Bermudez, C. A., Bhama, J. K., Shigemura, N., D'Cunha, J., & Subramaniam, K. (2018). Corrigendum to 'Extracorporeal Support During Bilateral Sequential Lung Transplantation in Patients with Pulmonary Hypertension: Risk factors and Outcomes' [Journal of Cardiothoracic and Vascular Anesthesia volume 31/2 (2017) 418-425]. Journal of cardiothoracic and vascular anesthesia, 32(4), 2034. https://doi.org/10.1053/j.jvca.2018.02.011
  • Tane, S., Noda, K., Toyoda, Y., & Shigemura, N. (2020). Bronchial-arterial-circulation-sparing Lung Preservation: A New Organ Protection Approach for Lung Transplantation. Transplantation, 104(3), 490–499. https://doi.org/10.1097/TP.0000000000002984
  • Shigemura N. (2020). Revisiting the link between PGD and BOS in lung transplantation: highlighting the role of tregs. Transplant international : official journal of the European Society for Organ Transplantation, 33(5), 497–499. https://doi.org/10.1111/tri.13595
  • Hayanga, J., Chan, E. G., Musgrove, K., Leung, A., Shigemura, N., & Hayanga, H. K. (2020). Extracorporeal Membrane Oxygenation in the Perioperative Care of the Lung Transplant Patient. Seminars in cardiothoracic and vascular anesthesia, 24(1), 45–53. https://doi.org/10.1177/1089253219896123
  • Kanaparthi, J., Kashem, M. A., Suryapalam, M., Zhao, H., Brann, S., Leotta, E., Minakata, K., Keshavamurthy, S., Shigemura, N., & Toyoda, Y. (2020). Prior and Perioperative Revascularization Does Not Affect Survival in Lung Transplant Patients. The Annals of thoracic surgery, 109(6), 1677–1683. https://doi.org/10.1016/j.athoracsur.2020.01.016
  • Haam, S., Noda, K., Philips, B. J., Harano, T., Sanchez, P. G., & Shigemura, N. (2020). Cyclosporin A Administration During Ex Vivo Lung Perfusion Preserves Lung Grafts in Rat Transplant Model. Transplantation, 10.1097/TP.0000000000003237. Advance online publication. https://doi.org/10.1097/TP.0000000000003237
  • Hayanga, J., Hayanga, H. K., Fugett, J. H., 2nd, Musgrove, K. A., Abbas, G., Ensor, C. R., Badhwar, V., & Shigemura, N. (2020). Contemporary look at extracorporeal membrane oxygenation as a bridge to reoperative lung transplantation in the United States - a retrospective study. Transplant international : official journal of the European Society for Organ Transplantation, 10.1111/tri.13617. Advance online publication. https://doi.org/10.1111/tri.13617
  • Shigemura N. Editorial: Transforming diagnostics in lung transplantation: From bronchoscopy to an A.I.-driven approach. Am J Respir Crit Care Med. 2020. [Epub ahead of print]  PMID:
  • Myers CN, Scott JH, Criner GJ, Cordova FC, Mamary AJ, Marchetti N, Shenoy KV, Galli JA, Mulhall PD, Brown JC, Shigemura N, Sehgal S. COVID-19 in lung transplant recipients. Transpl Infect Dis. 2020 [Epub ahead of print]  PMID:
  • Impact of Donor Age on IPF Patient Survival in Lung Transplantation S Dutta, A Kashem, G Sunagawa, S Brann, E Leotta, N Shigemura,Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S387, 2020. https://doi.org/10.1016/j.healun.2020.01.503
  • Do Public Health Service Increased Risk Donor Lungs Negatively Affect Survival Outcomes? J Lasky, A Kashem, SH Brann, E Leotta, S Gengo, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S382, 2020 https://doi.org/10.1016/j.healun.2020.01.489
  • Comparing the Use of Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass in Lung Transplantation P Ortiz, M Kashem, G Sunagawa, E Leotta, K Minakata, S Brann, N.Shigemura, Y.Toyoda The Journal of Heart and Lung Transplantation 39 (4), S104, 2020 https://doi.org/10.1016/j.healun.2020.01.962
  • Patients over 70 Years Old Show Acceptable Outcomes after Undergoing Concomitant Coronary Artery Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, S Brann, N Shigemura, E. Leotta, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S370-S371 , 2020 https://doi.org/10.1016/j.healun.2020.01.462
  • Younger Patients Show Acceptable Outcomes after Undergoing Concomitant Coronary Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, N Shigemura, S Brann, E. Leotta, Y. Toyod The Journal of Heart and Lung Transplantation 39 (4), S370, 2020 https://doi.org/10.1016/j.healun.2020.01.461
  • Assessing Lung Transplant Survival Following Donation after Cardiac Death: A Single Center Experience J Lasky, A Kashem, SH Brann, G Sunagawa, E Leotta, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S381, 2020 https://doi.org/10.1016/j.healun.2020.01.487
  • Wait or No Wait for Reducing Body Weight before Lung Transplant N Guynn, A Kashem, SH Brann, K Minakata, G Sunagawa, E Leotta, N Shigemura, Y Toyoda The Journal of Heart and Lung Transplantation 39 (4), S317-S318, 2020 https://doi.org/10.1016/j.healun.2020.01.716

Yoshiya Toyoda, MD

Peer-Reviewed Manuscripts

  • Ander EH, Kashem A, Zhao H, Montgomery K, Sunagawa G, Yanagida R, Shigemura N, Toyoda Y.  Lung Transplant Type and Donor Age in Idiopathic Pulmonary Fibrosis: A Single Center Study.  J Surg Res. 2022 Mar;271:125-136. doi: 10.1016/j.jss.2021.10.027. Epub 2021 Dec 11.
  • Van Der Rijst N, Mangukia C, Muhammad N, Sunagawa G, Brann S, Toyoda Y.  Determination of cardiovascular dysfunction before initiation of extracorporeal membrane oxygenation in septic shock.  Indian J Thorac Cardiovasc Surg. 2021 Jul;37(4):454-457. doi: 10.1007/s12055-020-01119-4. Epub 2021 Jan 26.
  • Mirza A, Romero CM, Toyoda Y, Hamad EA.  Identifying Patients With a Higher Potential for Recovery Post Left Ventricular Assist Device: A Single-Center Experience. Ochsner J. 2021 Winter;21(4):341-346. doi: 10.31486/toj.20.0160.
  • Timofeeva OA, Choe J, Alsammak M, Yoon EJ, Geier SS, Mathew L, McCollick A, Carney K, Au J, Diamond A, Galli JA, Shenoy K, Mamary A, Sehgal S, Mulhall P, Toyoda Y, Shigemura N, Cordova F, Criner G, Brown JC. Guiding therapeutic plasma exchange for antibody-mediated rejection treatment in lung transplant recipients - a retrospective study. Transpl Int. 2021 Apr;34(4):700-708. doi: 10.1111/tri.13825. Epub 2021 Feb 26.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y.  Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants. Interact Cardiovasc Thorac Surg. 2021 Oct 29;33(5):807-813. doi: 10.1093/icvts/ivab169.
  • Mangukia C, Sunagawa G, Brann S, Hamad E, Toyoda Y.  Modified technique for left ventricular assist device insertion in the setting of apical calcification.  JTCVS Tech. 2021 Apr 13;8:90-92. doi: 10.1016/j.xjtc.2021.04.007. eCollection 2021 Aug
  • Keshavamurthy S, Dulam V, Leung SW, Kashem MA, Toyoda Y.  Donor Pulmonary Vein Anomalies: What's in Your Toolbox? Ann Thorac Surg. 2021 Nov;112(5):e369-e371. doi: 10.1016/j.athoracsur.2021.02.015. Epub 2021 Feb 22.
  • Levy J, Kashem A, Sunagawa G, Zhao H, Minakata K, Keshavamurthy S, Brann S, Leotta E, Shigemura N, Toyoda Y.  Postoperative Bronchial Complications After Lung Transplantation Related to Anastomosis Suture.  Ann Thorac Surg. 2021 Aug 3:S0003-4975(21)01314-X. doi: 10.1016/j.athoracsur.2021.06.077. Online ahead of print.
  • Shigemura N, Cordova F, Hayanga AJ, Criner G, Toyoda Y.  Lung transplantation and coronavirus disease 2019 (COVID-19): a roadmap for the enduring pandemic. J Thorac Dis. 2021 Dec;13(12):6755-6759. doi: 10.21037/jtd-21-1667.
  • Mangukia C, Shigemura N, Stacey B, Sunagawa G, Muhammad N, Espinosa J, Kehara H, Yanagida R, Kashem MA, Minakata K, Toyoda Y. Donor quality assessment and size match in lung transplantation. Indian J Thorac Cardiovasc Surg. 2021 Sep;37(Suppl 3):401-415. doi: 10.1007/s12055-021-01251-9. Epub 2021 Sep 15.
  • Suryapalam M, Kashem M, Zhao H, Shigemura N, Toyoda Y, Keshavamurthy S. An Anthropometric Study of Lung Donors. Prog Transplant. 2021 Sep;31(3):211-218. doi: 10.1177/15269248211024611. Epub 2021 Jul 22.
  • Mangukia C, Sehgal S, Cordova F, Toyoda Y.  Lung transplantation-breathing a new life. Indian J Thorac Cardiovasc Surg. 2021 Sep;37(Suppl 3):357-358. doi: 10.1007/s12055-021-01257-3. Epub 2021 Sep 1.
  • Scott JH, Gordon M, Vender R, Pettigrew S, Desai P, Marchetti N, Mamary AJ, Panaro J, Cohen G, Bashir R, Lakhter V, Roth S, Zhao H, Toyoda Y, Criner G, Moores L, Rali P. Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism-Related Cardiac Arrest: A Systematic Review. Crit Care Med. 2021 May 1;49(5):760-769. doi: 10.1097/CCM.0000000000004828.
  • Mangukia C, Rali P, Desai P, Ku TJ, Brann S, Patel S, Sunagawa G, Minakata K, Kehara H, Toyoda Y. Pulmonary endarterectomy. Indian J Thorac Cardiovasc Surg. 2021 Nov;37(6):662-672. doi: 10.1007/s12055-021-01208-y. Epub 2021 Jun 29.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y. Clinical outcomes in patients with end-stage chronic obstructive pulmonary disease: Single versus bilateral lung transplants. Interactive Cardiovascular and Thoracic Surgery. 2021 (In press)
  • Levy J, Kashem MA, Sunagawa, Leotta E, Brann S, Minakata K, Toyoda Y. Post-operative operative bronchial complications following lung transplantation following lung transplantation related to anastomosis suture. Annals of Thoracic Surgery 2021 (In press) 
  • Keshavamurthy S, Dulam V, Kashem M, Leung S, Toyoda Y. Donor Pulmonary vein anomalies: What's in your toolbox? Accepted in Annals of Thoracic Surgery (In Press) 2021
  • Scott JH, Gordon M, Vender R, Pettigrew S, Desai P, Marchetti N, Mamary AJ, Panaro J, Cohen G, Bashir R, Lakhter V, Roth S, Zhao H, Toyoda Y, Criner G, Moores L, Rali P. Venoarterial Extracorporeal Membrane Oxygenation in Massive Pulmonary Embolism-Related Cardiac Arrest:  A Systematic Review. Critical Care Medicine 2021 (In Press)
  • Mazzei M, Keshavamurthy S, Timofeeva O, Toyoda Y. Management of the Sensitized Cardiac Transplantation Recipient. OBM Transplantation 2021;5(1), doi:10.21926/obm.transplant.2004130
  • Timofeeva OA, Choe J, Alsammak M, Yoon EJ, Geier SS, Mathew L, McCollick A, Carney K, Au J, Diamond A, Galli JA, Shenoy K, Mamary A, Seghal S, Mulhall P, Toyoda Y, Shigemura N, Cordova F, Criner G, Brown J. Transpl Int. 2021 Jan 20. doi: 10.1111/tri.13825.
  • Van Der Rijst, N, Mangukia C, Nadeem M, Sunagawa G, Brann S, Toyoda Y. Determination of cardiovascular dysfunction before initiation of extracorporeal membrane oxygenation in septic shock. Indian J Thorac Cardiovasc Surg 2021 In Press. https://doi.org/10.1007/s12055-020-01119-4
  • Mangukia C, Forfia P, Vaidya A, Williams V, Niman D, Rali P, Toyoda Y. Percutaneous coil embolization to manage pulmonary artery hemorrhage after distal endarterectomy. J Thorac Cardiovasc Surg Techniques. 2020;4:147-149.
  • Dulam V, Cooper JM, Gangireddy C, Kashem MA, Toyoda Y, Keshavamurthy S. From leads to leadless: A convoluted journey. HeartRhythm Case Rep. 2020 Jul 22;6(10):757-760.
  • Mangukia C, Brann S, Patel S, Jaffe F, Stewart J, Sunagawa G, Toyoda Y. Veno-arterial extracorporeal membrane oxygenationas a bridge to cytolytic therapy. Indian J Thorac Cardiovasc Surg. 2020 Jul 21:1-3
  • Shigemura N, Cordova F, Criner G, Toyoda Y. Current Precautions and Future Directions in Lung Transplantation during the COVID-19 Pandemic. Transpl Int. 2020 Jul 3
  • Dulam V, McCarthy J, Guvakov D, Kashem MA, Toyoda Y, Keshavamurthy S. 
  • Proximal Anastomotic Device Malfunction: Salvage Using Alternative Option. Innovations (Phila). 2020 Sep 16
  • Shigemura N, Toyoda Y. Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation. Transpl Int. 2020;33:347-355

Abstracts and Presentations 

  • Ahad Firoz, Mohammed Kashem, Manish Suryapalam, Huaqing Zhao, Shaira Jafar, Yoshiya Toyoda. Comparison of Body-mass Index on Survival Outcome Following Heart Transplantation: A UNOS Database Analysis. Control/Tracking Number: 21-A-15383-ACC Activity: 70th Annual Scientific Session of American College of Cardiology. May 15 – 17, 2021 in Atlanta, GA  
  • C. Mangukia, A. Kashem, J. Levy, N. Shigemura, Y. Toyoda. Splitting the Lungs in a Box for Single Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • G. Sunagawa, H. Kehara, M. Kashem, C. Mangukia, S. Brann, E. Leotta, R. Yanagida, K. Minakata, F. Cordova, Y. Toyoda, N. Shigemura. Single Lung Transplant Remains a Viable Alternative to Double Lung Transplantation for the Patients with Severe Secondary Pulmonary Hypertension. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • F. Ius, D. Van Raemdonck, M. Hartwig, B. Bottiger, G. Loor, D. Daoud, Q. Wei, M. Villavicencio-Theoduloz, A. Osho, S. Chandrashekaran, T. N. Machuca, A. Neyrinck, Y. Toyoda, M. A. Kashem, S. Huddleston, M. Myers, P. G. Sanchez, N. R. Ryssel, G. Warnecke. Effect of Surgical Exposure on Outcomes in Lung Transplantation: Insight from the International Multicenter Extracorporeal Life Support (ECLS) in Lung Transplantation Registry. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Donor Age, Recipient Age and Transplant Type: How Their Interplay Affects Lung Transplants. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Analysis of Increased Risk Donors Utilized in Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021 
  • A. S. Bussetty, M. A. Kashem, H. Zhao, G. Sunagawa, E. Leotta, N. Shigemura, R. Yanagida, S. H. Brann, K. Minakata, Y. Toyoda.. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Lung Transplantation: Is the Switch to Interrupted Suturing Worth it? The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • S. Mutyala, T. Tran, M. A. Kashem, H. Zhao, N. Shigemura, Y. Toyoda. Single Lung Transplantation in Patients under 50: Single Center and UNOS Analysis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • Amandeep Aneja, Anu Peter, Abul Kashem, Yoshiya Toyoda, Nirag Jhala. Unacceptable Donor Lungs Before and After Ex Vivo Lung Perfusion (EVLP): A Focus on Histologic Spectrum. 110th Annual Meeting (Virtual) United States and Canadian Academy of Pathology (USCAP). March 13-18, 2021.
  • S. Mutyala, M. A. Kashem, J. Kanaparthi, N. Shigemura, M. Suryapalam, E. Leotta, G. Sunagawa, K. Minakata, Y. Toyoda. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double-Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Study of Donor Age & Lung Transplant Type in Idiopathic Pulmonary Fibrosis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • Amandeep Aneja, Anu Peter, Abul Kashem, Yoshiya Toyoda, Nirag Jhala. Unacceptable Donor Lungs Before and After Ex Vivo Lung Perfusion (EVLP): A Focus on Histologic Spectrum. 110th Annual Meeting (Virtual) United States and Canadian Academy of Pathology (USCAP). March 13-18, 2021.
  • A. Bussetty, S. Mutyala, K. Montgomery, M. A. Kashem, H. Zhao, N. Shigemura, Y. Toyoda. A Single-Center Analysis of Survival Outcome between Donor after Cardiac Death and Donor after Brain Death. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. N. Tran, M. Kashem, H. Zhao, G. Sunagawa, N. Shigemura, R. Yanagida, H. Kehara, Y. Toyoda. Survival Outcomes of Redo Lung Transplantation: UNOS Database. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. Tran, M. Kashem, J. Kanaparthi, H. Zhao, S. Brann, E. Leotta, K. Minakata, R. Yanagida, G. Sunagawa, N. Shigemura, Y. Toyoda. Lung Transplant Survival Regarding Past and Concomitant Cardiac Revascularization. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • M. Suryapalam, M. Kashem, N. Shigemura, Y. Toyoda. Combined Heart-Lung Transplantation: UNOS Data Analysis for Long-Term Survival Outcome. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • A. Firoz, M. A. Kashem, S. Jafar, N. Shigemura, Y. Toyoda. Survival Outcome of Combined Heart and Lung Transplantation: Single Center vs. UNOS Data. Control/Tracking Number: 21-A-3944-ISHLT.  The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • M. Kashem, T. Tran, M. Suryapalam, V. Rakita, E. Hamad, K. Minakata, Y. Toyoda. Impact of Ventricular Assist Devices on Cardiac Transplant Recipient Survival Outcomes. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • M. A. Villavicencio, M. A. Kashem, G. Loor, M. Hartwig, B. Bottinger, F. Ius, D. Daoud, G. Warnecke, Q. Wei, S. Chandrashekaran, T. Machuca, D. Van Raemdonck, A. Neyrinck, S. Huddleston, M. Myers, P. Moonsamy, Y. Toyoda. Impact of Cold Ischemic Time on Morbidity and Mortality after Lung Transplantation. An Updated Analysis of the International Multicenter Extracorporeal Life Support in Lung Transplantation Registry. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • M. A. Kashem, G. Loor, M. Hartwig, M. Villavicencio-Theoduloz, A. L. Axtell, P. Sanchez, N. Ryssel, S. Huddleston, B. Bottiger, D. Daoud, H. Zhao, Q. Wei, A. S. Bussetty, F. Ius, G. Warnecke, T. Machuca, D. Van Raemdonck, A. E. Frick, A. Neyrinck, S. Chandrashekaran, Y. Toyoda. Interim Results - The Effect of Donor Type (Donor after Cardiac Death vs Donor after Brain Death) and Use of Intraoperative Extracorporeal Lung Support on Survival after Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021.
  • M. A. Kashem, G. Loor, M. Hartwig, M. Villavicencio-Theoduloz, A. L. Axtell, P. Sanchez, N. Ryssel, S. Huddleston, B. Bottiger, D. Daoud, H. Zhao, Q. Wei, A. S. Bussetty, F. Ius, G. Warnecke, T. Machuca, D. Van Raemdonck, A. E. Frick, A. Neyrinck, S. Chandrashekaran, Y. Toyoda. Extracorporeal Life Support Registry: Analysis of Ex Vivo Lung Perfusion Utilization in Donor after Cardiac Death and Donor after Brain Death. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021.
  • Kelly Montgomery, Mohammed A. Kashem, Huaquing Zhao, Norihisa Shigemura, Gengo Sunagawa, Eros H. Leotta, Roh Yanagida, Stacey Brann, Yoshiya Toyoda. Is the Switch to Interrupted Suturing Technique Worth It? The 16th Annual Meeting (Virtual) of Academic Surgical Congress, Feb 2-4, 2021.
  • E.H. Ander, Y. Toyoda, M.A. Kashem, H. Zhao, K.A. Montgomery, S. Mutyala, T.N. Tran, A.S. Bussetty. Lung Transplant Type & Donor Age in Idiopathic Pulmonary Fibrosis: A Single Center Experience. The 16th Annual Meeting (Virtual) of Academic Surgical Congress, Feb 2-4, 2021.
  • Bussetty AS, Kashem MA, Kanaparthi J, Zhao H, Sunagawa G, Leotta E, Shigemura N, Yanagida R, Brann SH, Minakata K, Toyoda Y. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 57th Annual Meeting of Society of Thoracic Surgery (virtual), January 29-31, 2021.
  • Impact of Total Time of Intraoperative Extracorporeal Life Support (ECLS) on Outcomes After Bilateral Lung Transplantation (LTx): Update From The International Multicenter ECLS in LTx Registry. MG Hartwig, G Loor, B Bottiger, D Daoud, Q Wei, F Ius, G Warnecke, MA. Villavicencio, K Drezek, S Chandrashekaran, TN Machuca, AE Frick, A Neyrinck, Y Toyoda, MA Kashem, S Huddleston, M Landeweer, D Van Raemdonck. 57th Annual Meeting of Society of Thoracic Surgery (virtual), January 29-31, 2021
  • E.H. Ander, Y. Toyoda, M.A. Kashem, H. Zhao, K.A. Montgomery, S. Mutyala, T.N. Tran, A.S. Bussetty. Increased Risk Donors Utilized in Lung Transplantation: A Single Center Experience. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021
  • Mutyala K, Kanaparthi J, Kashem MA, Shigemura N, Toyoda Y. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • Tran T, Kashem MA, Zhao H, Shigemura N, Toyoda Y. Redo-Lung Transplantation Survival Outcomes from UNOS Database. Abstract Number: 923789. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • Tran T, Kashem MA, Kanaparthi J, Zhao H, Brann S, Leotta E, Minakata K, Yanagida R, Sunagawa G, Shigemura N, Toyoda Y. Lung Transplant Survival with Past and Concomitant Cardiac Revascularization. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • M. Suryapalam, M.A. Kashem, G. Sunagawa, S. Brann, E. Leotta, N. Shigemura, Y. Toyoda. A Modern Large-scale Analysis of Heart Transplantation in Elderly Patients. American Heart Association, BCVS Meeting, 2020. Abstract 529. Circulation Research. 2020; 127; Suppl_1
  • Kanaparthi J, Kashem M, Suryapalam M, Toyoda Y. Despite prior results, heart transplant recipients over 70 have worse survival outcomes based on the 2019 united network for organ sharing database. Circulation 2020;142: A16930. American Heart Association Scientific Sessions 2020. Nov 17, 2020.
  • Y. Toyoda, A. Kashem, G. Sunagawa, S. Brann, K. Minakata, E. Leotta, N. Shigemura.  Survival Outcome of Single and Double Lung Transplantation in End-Stage COPD Patients. Virtual Room 115, 10:18 am. Lung Transplant and Basic Session, Oct-9, 2020. The 34th Annual Meeting of the European Association of Cardio-Thoracic Surgery. Barcelona, Spain (Virtual), October 8-11, 2020.
  • Kashem MA. Suryapalam M, Sunagawa G, Brann S, Minakata K, Leotta E, Shigemura N, Toyoda Y. Older Donor Lungs: Are They Viable Options Now for Organ Transplantation? American College of Surgery. Clinical Congress (Virtual)- ID 2158. October 3-7, 2020.
  • Dotan, Y., Vaidy, A., Shapiro, W. B., Zhao, H., Dass, C., Toyoda, Y., Marchetti, N., Shenoy, K., Cordova, F. C., Criner, G. J., & Mamary, A. J. (2018). Effect of Acute Exacerbation of Idiopathic Pulmonary Fibrosis on Lung Transplantation Outcome. Chest, 154(4), 818–826. https://doi.org/10.1016/j.chest.2018.06.027
  • Kumar, A., Keshavamurthy, S., Abraham, J. G., & Toyoda, Y. (2019). Massive Air Embolism Caused by a Central Venous Catheter During Extracorporeal Membrane Oxygenation. The journal of extra-corporeal technology, 51(1), 9–11.
  • Naito, N., Cook, K., Toyoda, Y., & Shigemura, N. (2018). Artificial Lungs for Lung Failure: JACC Technology Corner. Journal of the American College of Cardiology, 72(14), 1640–1652. https://doi.org/10.1016/j.jacc.2018.07.049
  • Lacharite-Roberge, A. S., Raza, F., Bashir, R., Dass, C. A., Moser, G. W., Auger, W. R., Toyoda, Y., Forfia, P. R., & Vaidya, A. (2019). Case series of seven women with uterine fibroids associated with venous thromboembolism and chronic thromboembolic disease. Pulmonary circulation, 9(1), 2045894018803873. https://doi.org/10.1177/2045894018803873
  • Carro, S. E., Essex, D. W., Alsammak, M., Bains, A., Toyoda, Y., & Keshavamurthy, S. (2019). Mediastinal Lymphoma Presenting in Cardiogenic Shock with Superior Vena Cava Syndrome in a Primigravida at Full Term: Salvage Resection after Prolonged Extracorporeal Life Support. Case reports in oncology, 12(2), 401–410. https://doi.org/10.1159/000499195
  • Raza, F., Vaidya, A., Lacharite-Roberge, A. S., Lakhter, V., Al-Maluli, H., Ahsan, I., Boodram, P., Dass, C., Rogers, F., Keane, M. G., Weaver, S., Bashir, R., Toyoda, Y., & Forfia, P. (2018). Initial clinical and hemodynamic results of a regional pulmonary thromboendarterectomy program. The Journal of cardiovascular surgery, 59(3), 428–437. https://doi.org/10.23736/S0021-9509.17.10188-6
  • Shigemura, N., & Toyoda, Y. (2020). Elderly patients with multiple comorbidities: insights from the bedside to the bench and programmatic directions for this new challenge in lung transplantation. Transplant international : official journal of the European Society for Organ Transplantation, 33(4), 347–355. https://doi.org/10.1111/tri.13533
  • Tane, S., Noda, K., Toyoda, Y., & Shigemura, N. (2020). Bronchial-arterial-circulation-sparing Lung Preservation: A New Organ Protection Approach for Lung Transplantation. Transplantation, 104(3), 490–499. https://doi.org/10.1097/TP.0000000000002984
  • Ta, J., Mishra, S., Vaidya, A., Forfia, P. R., Toyoda, Y., Auger, W. R., Salamanca-Padilla, Y. Y., & Morewood, G. H. (2020). Cangrelor and Heparin for Pulmonary Thromboendarterectomy in Heparin-Induced Thrombocytopenia. The Annals of thoracic surgery, S0003-4975(20)30269-1. Advance online publication. https://doi.org/10.1016/j.athoracsur.2020.01.051
  • Kanaparthi, J., Kashem, M. A., Suryapalam, M., Zhao, H., Brann, S., Leotta, E., Minakata, K., Keshavamurthy, S., Shigemura, N., & Toyoda, Y. (2020). Prior and Perioperative Revascularization Does Not Affect Survival in Lung Transplant Patients. The Annals of thoracic surgery, 109(6), 1677–1683. https://doi.org/10.1016/j.athoracsur.2020.01.016
  • Boova, R., Banerjee, S., Kashem, A., Das, A., Zimmerman, H., Jennings, R., Minakata, K., & Toyoda, Y. (2020). Computed tomography angiography is not accurate in predicting surgical prosthetic aortic valve implant size. Surgery, 167(2), 499–503. https://doi.org/10.1016/j.surg.2019.06.022
  • Timofeeva, O. A., Alvarez, R., Pelberg, J., Yoon, E., Alsammak, M., Geier, S. S., Ruggia-Check, C., Hassler, J., Hoosain, J., Brisco, M. A., Afari-Armah, N., Rakita, V., Brann, S., Keshavamurthy, S., Gomez-Abraham, J., Minakata, K., Toyoda, Y., & Hamad, E. (2020). Serum dilutions as a predictive biomarker for peri-operative desensitization: An exploratory approach to transplanting sensitized heart candidates. Transplant immunology, 60, 101274. https://doi.org/10.1016/j.trim.2020.101274
  • Shigemura N*, Cordova F, Criner G, Toyoda Y. Current precautions and future directions in lung transplantation during the COVID-19 pandemic. Transplant Int. 2020. [Epub ahead of print]  PMID:  (Shigemura,N. Corresponding Author)
  • Impact of Donor Age on IPF Patient Survival in Lung Transplantation
  • S Dutta, A Kashem, G Sunagawa, S Brann, E Leotta, N Shigemura,Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S387, 2020. https://doi.org/10.1016/j.healun.2020.01.503
  • Do Public Health Service Increased Risk Donor Lungs Negatively Affect Survival Outcomes?
  • J Lasky, A Kashem, SH Brann, E Leotta, S Gengo, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S382, 2020 https://doi.org/10.1016/j.healun.2020.01.489
  • Comparing the Use of Extracorporeal Membrane Oxygenation and Cardiopulmonary Bypass in Lung Transplantation P Ortiz, M Kashem, G Sunagawa, E Leotta, K Minakata, S Brann, N.Shigemura, Y.Toyoda The Journal of Heart and Lung Transplantation 39 (4), S104, 2020 https://doi.org/10.1016/j.healun.2020.01.962
  • Patients over 70 Years Old Show Acceptable Outcomes after Undergoing Concomitant Coronary Artery Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, S Brann, N Shigemura, E. Leotta, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S370-S371 , 2020 https://doi.org/10.1016/j.healun.2020.01.462
  • Younger Patients Show Acceptable Outcomes after Undergoing Concomitant Coronary Bypass Grafting with Lung Transplantation D DeFazio, M Kashem, G Sunagawa, K Minakata, N Shigemura, S Brann, E. Leotta, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S370, 2020 https://doi.org/10.1016/j.healun.2020.01.461
  • Assessing Lung Transplant Survival Following Donation after Cardiac Death: A Single Center Experience J Lasky, A Kashem, SH Brann, G Sunagawa, E Leotta, N Shigemura, Y. Toyoda The Journal of Heart and Lung Transplantation 39 (4), S381, 2020 https://doi.org/10.1016/j.healun.2020.01.487
  • Wait or No Wait for Reducing Body Weight before Lung Transplant N Guynn, A Kashem, SH Brann, K Minakata, G Sunagawa, E Leotta, N Shigemura, Y Toyoda The Journal of Heart and Lung Transplantation 39 (4), S317-S318, 2020 https://doi.org/10.1016/j.healun.2020.01.716
  • VenoArterial Extra-Corporeal Membrane Oxygenation as bridge to cytolytic therapy. Mangukia C, Patel S, Brann S, Jaffe F, Sunagawa G, Toyoda Y. Accepted for publication: Indian Journal of Thoracic and Cardiovascular Surgery: IJTC-D-20-00067R2

Roh Yanagida, MD

Peer-Reviewed Manuscripts 

  • Mangukia C, Shigemura N, Stacey B, Sunagawa G, Muhammad N, Espinosa J, Kehara H, Yanagida R, Kashem MA, Minakata K, Toyoda Y.  Donor quality assessment and size match in lung transplantation.  Indian J Thorac Cardiovasc Surg. 2021 Sep;37(Suppl 3):401-415. doi: 10.1007/s12055-021-01251-9. Epub 2021 Sep 15.
  • Ander EH, Kashem A, Zhao H, Montgomery K, Sunagawa G, Yanagida R, Shigemura N, Toyoda Y.  Lung Transplant Type and Donor Age in Idiopathic Pulmonary Fibrosis: A Single Center Study. J Surg Res. 2022 Mar;271:125-136. doi: 10.1016/j.jss.2021.10.027. Epub 2021 Dec 11.
  • Mutyala S, Kashem MA, Kanaparthi J, Sunagawa G, Suryapalam M, Leotta E, Minakata K, Brann S, Shigemura N, Toyoda Y. Clinical outcomes in patients with end-stage chronic obstructive pulmonary disease: Single versus bilateral lung transplants. Interactive Cardiovascular and Thoracic Surgery. 2021 (In press)
  • Levy J, Kashem MA, Sunagawa, Leotta E, Brann S, Minakata K, Toyoda Y. Post-operative operative bronchial complications following lung transplantation following lung transplantation related to anastomosis suture. Annals of Thoracic Surgery 2021 (In press) 

Abstracts and Presentations

  • G. Sunagawa, H. Kehara, M. Kashem, C. Mangukia, S. Brann, E. Leotta, R. Yanagida, K. Minakata, F. Cordova, Y. Toyoda, N. Shigemura. Single Lung Transplant Remains a Viable Alternative to Double Lung Transplantation for the Patients with Severe Secondary Pulmonary Hypertension. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Donor Age, Recipient Age and Transplant Type: How Their Interplay Affects Lung Transplants. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Analysis of Increased Risk Donors Utilized in Lung Transplantation. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021 
  • A. S. Bussetty, M. A. Kashem, H. Zhao, G. Sunagawa, E. Leotta, N. Shigemura, R. Yanagida, S. H. Brann, K. Minakata, Y. Toyoda.. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • K. Montgomery, Y. Toyoda, M. A. Kashem, G. Sunagawa, N. Shigemura, R. Yanagida, K. Minakata, S. Brann, E. Leotta. Lung Transplantation: Is the Switch to Interrupted Suturing Worth it? The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • S. Mutyala, M. A. Kashem, J. Kanaparthi, N. Shigemura, M. Suryapalam, E. Leotta, G. Sunagawa, K. Minakata, Y. Toyoda. Impact of Pulmonary Artery Pressure on Survival Outcome of Single- and Double-Lung Transplantation in Chronic Obstructive Pulmonary Disease Patients. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • E. H. Ander, M. A. Kashem, H. Zhao, N. Shigemura, G. Sunagawa, S. H. Brann, E. Leotta, R. Yanagida, Y. Toyoda. A Single Center Study of Donor Age & Lung Transplant Type in Idiopathic Pulmonary Fibrosis. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • H. Kehara, R. Yanagida, A. Kashem, C. Mangukia, G. Sunagawa, S. Brann, E. Leotta, R. Boova, N. Shigemura, K. Minakata, Y. Toyoda.  Outcomes after Lung Re-Transplantation: A Single-Center Experience. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • T. Tran, M. Kashem, J. Kanaparthi, H. Zhao, S. Brann, E. Leotta, K. Minakata, R. Yanagida, G. Sunagawa, N. Shigemura, Y. Toyoda. Lung Transplant Survival Regarding Past and Concomitant Cardiac Revascularization. The 41st Annual ISHLT Meeting (virtual) and Scientific Sessions. April 24-28, 2021
  • Kelly Montgomery, Mohammed A. Kashem, Huaquing Zhao, Norihisa Shigemura, Gengo Sunagawa, Eros H. Leotta, Roh Yanagida, Stacey Brann, Yoshiya Toyoda. Is the Switch to Interrupted Suturing Technique Worth It? The 16th Annual Meeting (Virtual) of Academic Surgical Congress, Feb 2-4, 2021.
  • Bussetty AS, Kashem MA, Kanaparthi J, Zhao H, Sunagawa G, Leotta E, Shigemura N, Yanagida R, Brann SH, Minakata K, Toyoda Y. Extracorporeal Membrane Oxygenation in Lung Transplantation: Superior to Cardiopulmonary Bypass and Comparable to Off-Pump Strategy. The 57th Annual Meeting of Society of Thoracic Surgery (virtual), January 29-31, 2021.
  • Tran T, Kashem MA, Kanaparthi J, Zhao H, Brann S, Leotta E, Minakata K, Yanagida R, Sunagawa G, Shigemura N, Toyoda Y. Lung Transplant Survival with Past and Concomitant Cardiac Revascularization. The 57th Annual Meeting (Virtual) of Society of Thoracic Surgery, Jan 29 – 31, 2021.
  • Yanagida, R., Seethamraju, H., Davenport, D. L., Tribble, T. A., Zwischenberger, J. B., & Hoopes, C. W. (2019). Bridging to lung transplantation with double-lumen venovenous extracorporeal membrane oxygenation. The International journal of artificial organs, 42(11), 621–627. https://doi.org/10.1177/0391398819851516
  • Yanagida, R., Rajagopalan, N., Davenport, D. L., Tribble, T. A., Bradley, M. A., & Hoopes, C. W. (2018). Delayed sternal closure does not reduce complications associated with coagulopathy and right ventricular failure after left ventricular assist device implantation. Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 21(1), 46–51. https://doi.org/10.1007/s10047-017-0996-z
  • Yanagida, R., Anstead, M., Seethamraju, H., & Hoopes, C. W. (2020). Pediatric Bilateral Lung Transplantation From a Donor With Thermal Inhalation Injury. Progress in transplantation (Aliso Viejo, Calif.), 30(1), 67–68. https://doi.org/10.1177/1526924819893311